Alexander Rudensky (born August 21, 1956) is an immunologist at

Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute– ...

known for his research on

regulatory T cells The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease. Treg cells are immunosu ...

and the

transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The fu ...

Foxp3 FOXP3 ( forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of ...

Career

Rudensky received his

Candidate of Sciences Candidate of Sciences (russian: кандидат наук, translit=kandidat nauk) is the first of two doctoral level scientific degrees in Russia and the Commonwealth of Independent States. It is formally classified as UNESCO's ISCED level 8, "do ...

degree in 1986 from the Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, and completed his postdoctoral work at the

Yale School of Medicine The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...

. He is now the Chair of the Immunology Program and Director of the Ludwig Center at Memorial Sloan Kettering, as well as a professor at the

Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...

Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...

, Gerstner School of Graduate Studies, and Weill-Cornell Medical School. In a 2003 paper, Rudensky and colleagues showed that Foxp3 programs regulatory T cell development. His lab continues to investigate the molecular mechanisms underlying regulatory T cell activity, and the role these cells play in autoimmunity, tumor immunity, and immunity to infections.

Awards

* 2012 Member of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

* 2015 Member of the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...

* 2015

William B. Coley Award The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists who have made outstanding achievements in the fields of basic and tumor immunology and whose w ...

* 2017

Crafoord Prize The Crafoord Prize is an annual science prize established in 1980 by Holger Crafoord, a Swedish industrialist, and his wife Anna-Greta Crafoord. The Prize is awarded in partnership between the Royal Swedish Academy of Sciences and the Crafoord Foun ...

in Polyarthritis * 2018

Vilcek Prize The Vilcek Foundation raises awareness of immigrant contributions to the United States, and fosters appreciation of the arts and sciences. The foundation's flagship programs include the Vilcek Foundation Prizes, which recognize and support immigra ...

in Biomedical Science

References

External links

mskcc.org
* {{US-biologist-stub American microbiologists 1956 births Living people Yale School of Medicine alumni Members of the National Academy of Medicine