Alev Erisir
   HOME

TheInfoList



OR:

Alev Erisir is a Turkish-American
neuroscientist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, Biological neural network, n ...
. She is a Professor of Psychology and the Department Chair at the
University of Virginia The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United S ...
in
Charlottesville Charlottesville, colloquially known as C'ville, is an independent city in the Commonwealth of Virginia. It is the county seat of Albemarle County, which surrounds the city, though the two are separate legal entities. It is named after Queen Cha ...
. Her primary research areas include synaptic connectivity in the visual and taste systems, neuronal circuit
plasticity Plasticity may refer to: Science * Plasticity (physics), in engineering and physics, the propensity of a solid material to undergo permanent deformation under load * Neuroplasticity, in neuroscience, how entire brain structures, and the brain it ...
, and ultrastructural
neuroanatomy Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defin ...
.


Early life and education

Erisir was born in
Kastamonu Kastamonu is the capital district of the Kastamonu Province, Turkey. According to the 2000 census, population of the district is 102,059 of which 64,606 live in the urban center of Kastamonu. (Population of the urban center in 2010 is 91,012.) The ...
, Turkey. Her father was stationed in Kastamonu as a malaria eradication doctor. As an infant, Erisir moved with her family to Canakkale, Turkey, where she grew up until the age of 11. The family then moved to
Istanbul Istanbul ( , ; tr, İstanbul ), formerly known as Constantinople ( grc-gre, Κωνσταντινούπολις; la, Constantinopolis), is the List of largest cities and towns in Turkey, largest city in Turkey, serving as the country's economic, ...
, Turkey, where Erisir completed her secondary education. In 1986, following high school graduation, Erisir attended
Istanbul University , image = Istanbul_University_logo.svg , image_size = 200px , latin_name = Universitas Istanbulensis , motto = tr, Tarihten Geleceğe Bilim Köprüsü , mottoeng = Science Bridge from Past to the Future , established = 1453 1846 1933 ...
School of Medicine and received her MD. In 1996, Erisir graduated from the
State University of New York at Stony Brook Stony Brook University (SBU), officially the State University of New York at Stony Brook, is a public research university in Stony Brook, New York. Along with the University at Buffalo, it is one of the State University of New York system's ...
with a PhD in Behavioral Neuroscience.


Research and career

Erisir completed postdoctoral training at
New York University New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then-Secretary of the Treasury Albert Gallatin. In 1832, the ...
(NYU)
Center for Neural Science Center or centre may refer to: Mathematics *Center (geometry), the middle of an object * Center (algebra), used in various contexts ** Center (group theory) ** Center (ring theory) * Graph center, the set of all vertices of minimum eccentricity ...
. She completed her training under the guidance of Chiye Aoki. In Aoki's laboratory, Professor Erisir trained specifically in Electron Microscopy. After completing her training at NYU, Erisir completed a one-year postdoctoral appointment at
New York Medical College New York Medical College (NYMC or New York Med) is a private medical school in Valhalla, New York. Founded in 1860, it is a member of the Touro College and University System. NYMC offers advanced degrees through its three schools: the School o ...
(NYMC)  in the department of Physiology. Following her time at NYMC, Erisir returned to NYU this time as a Research Assistant Professor. In 2000, Erisir started working at
University of Virginia The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United S ...
(UVA) as an assistant professor. In 2013, she was granted professor status at UVA. During her time at UVA, Erisir has served in several administrative roles, including co-director of the neuroscience graduate program, director of the cognitive science program, and director of the neuroscience undergraduate program. In 2016, she was appointed to be the chair of the psychology department at UVA. At UVA, Erisir's research has consisted of investigating ocular dominance column plasticity using several different techniques, brain stem gustatory circuitry, the aging brain and its pathology, and three-dimensional connectomics. Erisir conducts studies on cellular mechanisms within the aging brain and neurodegenerative diseases such as
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
. Her work examines the relationship between hyperactive
oligodendrocyte Oligodendrocytes (), or oligodendroglia, are a type of neuroglia whose main functions are to provide support and insulation to axons in the central nervous system of jawed vertebrates, equivalent to the function performed by Schwann cells in the ...
s and cognitive impairments in Alzheimer's mouse models. Additionally, Erisir's research examines proteins such as
beta-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which i ...
and
tau Tau (uppercase Τ, lowercase τ, or \boldsymbol\tau; el, ταυ ) is the 19th letter of the Greek alphabet, representing the voiceless dental or alveolar plosive . In the system of Greek numerals, it has a value of 300. The name in English ...
that result in the loss of
synaptic plasticity In neuroscience, synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. Since memories are postulated to be represented by vastly interconnected neural circuit ...
. In 2008, Erisir received a University of Virginia Mead Grant, which funded an opportunity for Erisir to take undergraduates to the annual Society of Neuroscience conference. In 2010, she mentored a research project that investigated rodent neural circuitry between the brainstem and the oral cavity. This project was selected by the University of Virginia to receive the "Double Hoo" Grant.


Selected publications

* * * * * * * * * * * * * * *


References

{{DEFAULTSORT:Erisir, Alev Year of birth missing (living people) Living people People from Kastamonu Istanbul University Faculty of Medicine alumni Turkish women physicians Turkish physicians Stony Brook University alumni American women psychologists University of Virginia School of Medicine faculty American women neuroscientists American academics of Turkish descent 21st-century American women