Alan D. Grossman, is an American microbiologist; he is currently the Praecis Professor of Biology and served head of the Department of Biology at the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...

from 2014-2022. He is a member of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

and the

American Academy of Arts & Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States of America, United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bow ...

Education

Grossman received a Bachelor of Arts in biochemistry from

Brown University Brown University is a private research university in Providence, Rhode Island. Brown is the seventh-oldest institution of higher education in the United States, founded in 1764 as the College in the English Colony of Rhode Island and Providenc ...

in 1979. He earned his Ph.D. at the

University of Wisconsin–Madison A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities ty ...

in 1984. Grossman completed a postdoctoral fellowship in the Department of Cellular and Developmental Biology at

Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

before joining MIT's biology department in 1988.

Career

Initially, his research was focused on characterization of bacterial

chromosome segregation Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation ...

. His group was among the first that identified the Spo0J protein, the homologue of ParB, responsible for the process of chromosome segregation in

B. subtilis ''Bacillus subtilis'', known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants, humans and marine sponges. As a member of the genus ''Bacillus' ...

. He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ''

ParS Pars may refer to: * Fars Province of Iran, also known as Pars Province * Pars (Sasanian province), a province roughly corresponding to the present-day Fars, 224–651 * ''Pars'', for ''Persia'' or ''Iran'', in the Persian language * Pars News A ...

''. In 2006, Grossman received a life-saving

heart transplant A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. , the most common proce ...

. He has discussed the experience publicly and encouraged others to consider

organ donation Organ donation is the process when a person allows an organ of their own to be removed and transplanted to another person, legally, either by consent while the donor is alive or dead with the assent of the next of kin. Donation may be for re ...

References

External links

* Year of birth missing (living people) Living people American microbiologists Massachusetts Institute of Technology School of Science faculty Members of the United States National Academy of Sciences Brown University alumni University of Wisconsin–Madison alumni {{US-biologist-stub