Akhil Chandra Banerjea
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Akhil Chandra Banerjea (born 1956) is an Indian virologist and is currently the Director at Institute of Advanced Virology, Kerala. He was earlier an Emeritus Scientist at the
National Institute of Immunology, India National Institute of Immunology (NII) is an autonomous research institute located in New Delhi, under the Department of Biotechnology (DBT) for research in immunology. NII was established on 24 June 1981, with Prof. M. G. K. Menon as Chairman ...
. Known for his studies on
viral pathogenesis Viral pathogenesis is the study of the process and mechanisms by which viruses cause diseases in their target hosts, often at the cellular or molecular level. It is a specialized field of study in virology. Pathogenesis is a qualitative descriptio ...
and
gene therapy Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DN ...
, Banerjea is an elected fellow of the
National Academy of Sciences, India The National Academy of Sciences, India, established in 1930, is the oldest science academy in India. It is located in Prayagraj, Uttar Pradesh. Prof. Meghnad Saha was the founder president. Fellows *Suddhasatwa Basu * Sudha Bhattacharya * Ch ...
and the
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi for Indian scientists in all branches of science and technology. In August 2019, Dr. Chandrima Shaha was appointed as the president of Indian National Science Academ ...
. The
Department of Biotechnology The Department of Biotechnology (DBT) is an Indian government department, under the Ministry of Science and Technology responsible for administrating development and commercialisation in the field of modern biology and biotechnology in India. It ...
of the Government of India awarded him the
National Bioscience Award for Career Development The National Bio-science Award for Career Development or N-BIOS Prize is an Indian science award for recognizing excellence and promoting research in bio-sciences disciplines. It was instituted in 1999 by the Department of Biotechnology of the Gov ...
, one of the highest Indian science awards, for his contributions to biosciences in 2001.


Biography

Akhil C. Banerjea, born in 1956 in the Indian state of
West Bengal West Bengal (, Bengali: ''Poshchim Bongo'', , abbr. WB) is a state in the eastern portion of India. It is situated along the Bay of Bengal, along with a population of over 91 million inhabitants within an area of . West Bengal is the fourt ...
, did his under-graduate studies at
Gorakhpur University DDU Gorakhpur University (simply known as University of Gorakhpur) is located in Gorakhpur, Uttar Pradesh, Gorakhpur, Uttar Pradesh. The University of Gorakhpur is a teaching and residential-cum-affiliating University. It is about . from the d ...
and after earning a BSc, he continued his studies at
G. B. Pant University of Agriculture and Technology G. B. Pant University of Agriculture, also known as Pantnagar University, is the first agricultural university of India. It was inaugurated by Jawahar Lal Nehru on 17 November 1960 as the "Uttar Pradesh Agricultural University" (UPAU). Later the ...
to obtain a master's degree (MSc). Subsequently, he joined
National Institute of Virology The National Institute of Virology in Pune, India is an Indian virology research institute and part of the Indian Council of Medical Research (ICMR). It was previously known as 'Virus Research Centre' and was founded in collaboration with the ...
for his doctoral research in
virology Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), ...
which earned him a PhD from
Savitribai Phule Pune University Savitribai Phule Pune University (SPPU), formerly the University of Poona, is a collegiate public state university located in the city of Pune, India. It was established in 1949, and is spread over a campus in the neighbourhood of Ganeshk ...
. His post-doctoral work was in the US where he did research at
Duke University Hospital Duke University Hospital is a 957-acute care bed academic tertiary care facility located in Durham, North Carolina. Established in 1930, it is the flagship teaching hospital for the Duke University Health System, a network of physicians and hosp ...
, simultaneously working as an assistant professor from 1984 to 1990 and spent the next four years (1990–94) at the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
as a senior staff fellow. On his return to India, he joined the National Institute of Immunology and chaired the department of virology for a while. After superannuation from service, he continues his association with the institute as an Emeritus Scientist. In between, he had a two-year stint at Colorado State University as a visiting professor during 2002–04.


Legacy

Banerjea's research has been focusing on
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
with special emphasis on the
pathogenesis Pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. The word comes from Greek πάθος ''pat ...
, host-gene interactions and the genetic as well as the functional characterization of
HIV-1 The subtypes of HIV include two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the sooty mangabey, ...
. He worked on developing catalytic nucleic acids for antiviral uses and later, at
Colorado State University Colorado State University (Colorado State or CSU) is a public land-grant research university in Fort Collins, Colorado. It is the flagship university of the Colorado State University System. Colorado State University is classified among "R1: ...
, his research was centered around conversion of
Small interfering RNA Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules, typically 20-24 (normally 21) base pairs in length, similar to miRNA, and operating wi ...
(siRNA) into stem cells which was reported inn 2003 by ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
''; the approach was subsequently put on clinical trial in the US. He has also worked on the effect of lentiviral vectors, stem cells, catalytic nucleic acids and siRNA for developing gene therapy against HIV/AIDS as well as the study of host or viral genes in understanding the HIV/AIDS pathogenesis. His studies have been documented by way of a number of articles and
ResearchGate ResearchGate is a European commercial social networking site for scientists and researchers to share papers, ask and answer questions, and find collaborators. According to a 2014 study by ''Nature'' and a 2016 article in ''Times Higher Education'' ...
, an online repository of scientific articles, has listed 103 of them. He has delivered key note or invited speeches at seminars and conferences at places such as
Albert Einstein College of Medicine Albert Einstein College of Medicine is a research-intensive medical school located in the Morris Park neighborhood of the Bronx in New York City. Founded in 1953, Einstein operates as an independent degree-granting institution as part of t ...
,
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
,
University of California, Los Angeles The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California St ...
,
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
,
Drexel University Drexel University is a private research university with its main campus in Philadelphia, Pennsylvania. Drexel's undergraduate school was founded in 1891 by Anthony J. Drexel, a financier and philanthropist. Founded as Drexel Institute of Art, S ...
and
National University of Singapore The National University of Singapore (NUS) is a national public research university in Singapore. Founded in 1905 as the Straits Settlements and Federated Malay States Government Medical School, NUS is the oldest autonomous university in the c ...
. He has also mentored many research scholars in their studies.


Awards and honors

The
Department of Biotechnology The Department of Biotechnology (DBT) is an Indian government department, under the Ministry of Science and Technology responsible for administrating development and commercialisation in the field of modern biology and biotechnology in India. It ...
of the Government of India awarded Banerjea the
National Bioscience Award for Career Development The National Bio-science Award for Career Development or N-BIOS Prize is an Indian science award for recognizing excellence and promoting research in bio-sciences disciplines. It was instituted in 1999 by the Department of Biotechnology of the Gov ...
, one of the highest Indian science awards in 2001. The same year, he was elected as a fellow by the
National Academy of Sciences, India The National Academy of Sciences, India, established in 1930, is the oldest science academy in India. It is located in Prayagraj, Uttar Pradesh. Prof. Meghnad Saha was the founder president. Fellows *Suddhasatwa Basu * Sudha Bhattacharya * Ch ...
. He is also a recipient of the National Foreign-Associateship of the Department of Biotechnology and the Shakuntala Amir Chand Award of the
Indian Council of Medical Research The Indian Council of Medical Research (ICMR), the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest and largest medical research bodies in the world. The ICMR is funded by the Gove ...
. The
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi for Indian scientists in all branches of science and technology. In August 2019, Dr. Chandrima Shaha was appointed as the president of Indian National Science Academ ...
elected him as a fellow in 2012; INSA would honor him again in 2016 with the Senior Scientist Award.


Selected bibliography

* * * * *


See also

*
RNA interference RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by o ...
*
Gene knockdown Gene knockdown is an experimental technique by which the expression of one or more of an organism's genes is reduced. The reduction can occur either through genetic modification or by treatment with a reagent such as a short DNA or RNA oligonucleot ...


References


External links

* {{DEFAULTSORT:Banerjea, Akhil Chandra N-BIOS Prize recipients 20th-century Indian biologists Indian scientific authors Living people 1956 births Scientists from West Bengal Fellows of the Indian National Science Academy Indian molecular biologists Fellows of The National Academy of Sciences, India Indian virologists Deen Dayal Upadhyay Gorakhpur University alumni Savitribai Phule Pune University alumni