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Brodmann area 6 (BA6) is part of the
frontal Front may refer to: Arts, entertainment, and media Films * ''The Front'' (1943 film), a 1943 Soviet drama film * ''The Front'', 1976 film Music *The Front (band), an American rock band signed to Columbia Records and active in the 1980s and ea ...
cortex in the
human brain The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the ...
. Situated just anterior to the
primary motor cortex The primary motor cortex (Brodmann area 4) is a brain region that in humans is located in the dorsal portion of the frontal lobe. It is the primary region of the motor system and works in association with other motor areas including premotor co ...
( BA4), it is composed of the premotor cortex and, medially, the supplementary motor area (SMA). This large area of the frontal cortex is believed to play a role in planning complex, coordinated movements. Brodmann area 6 is also called agranular frontal area 6 in humans because it lacks an internal granular cortical layer (layer IV). It is a subdivision of the
cytoarchitecturally Cytoarchitecture (Ancient Greek language, Greek ''wiktionary:κύτος#Ancient_Greek, κύτος''= "cell" + ''wiktionary:ἀρχιτέκτων#Ancient_Greek, ἀρχιτεκτονική''= "architecture"), also known as cytoarchitectonics, is th ...
defined precentral region of cerebral cortex. In the human brain, it is located on the portions of the precentral gyrus that are not occupied by Brodmann area 4; furthermore, BA6 extends onto the caudal portions of the superior frontal and middle frontal gyri. It extends from the cingulate sulcus on the medial aspect of the hemisphere to the
lateral sulcus In neuroanatomy, the lateral sulcus (also called Sylvian fissure, after Franciscus Sylvius, or lateral fissure) is one of the most prominent features of the human brain. The lateral sulcus is a deep fissure in each hemisphere that separates the ...
on the lateral aspect. It is bounded rostrally by the granular frontal region and caudally by the gigantopyramidal area 4 (Brodmann, 1909).


In animals

Brodmann area 6 is a cytoarchitecturally defined portion of the frontal lobe of the guenon. Brodmann-1909 regarded it as topographically and cytoarchitecturally homologous to the human agranular frontal area 6 and noted that, in the monkey, area 4 is larger than area 6, whereas, in the human, area 6 is larger than area 4. Distinctive features (Brodmann-1905): It is thick relative to other cortical areas; the transition from cortex to subcortical
white matter White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution ...
is gradual; cell layers are indistinct; and the internal granular layer (IV) is absent.


Image

File:Brodmann area 6 animation small.gif, Animation. File:Brodmann area 6 frontal.jpg, front view. File:Brodmann area 6 lateral.jpg, Lateral view. File:Brodmann area 6 medial.jpg, Medial view.


See also

* Brodmann area *
List of regions in the human brain The human brain anatomical regions are ordered following standard neuroanatomy hierarchies. Functional, connective, and developmental regions are listed in parentheses where appropriate. Hindbrain (rhombencephalon) Myelencephalon * Med ...
* Korbinian Brodmann


References


External links

* – agranular frontal area 6 * – Brodmann area 6 {{Prosencephalon 06 Frontal lobe