Agracetus
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The Agracetus Campus of Monsanto Company is a
soybean The soybean, soy bean, or soya bean (''Glycine max'') is a species of legume native to East Asia, widely grown for its edible bean, which has numerous uses. Traditional unfermented food uses of soybeans include soy milk, from which tofu a ...
transformation Transformation may refer to: Science and mathematics In biology and medicine * Metamorphosis, the biological process of changing physical form after birth or hatching * Malignant transformation, the process of cells becoming cancerous * Tran ...
laboratory. It has over 21,700 employees worldwide, and an annual
revenue In accounting, revenue is the total amount of income generated by the sale of goods and services related to the primary operations of the business. Commercial revenue may also be referred to as sales or as turnover. Some companies receive reven ...
of US$11.365 billion reported for 2008. The first successful
genetically engineered Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including t ...
crop ever produced for the commercial market was the '' Roundup Ready soybean'', produced at Agracetus in 1991, and was one of fourteen successful transformation events. Scientists there used gold bead gene transfer technology coupled with the
β-Glucuronidase Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. Human β-glucuronidase is a type of glucuronidase (a member of glycosidase Family 2) that catalyzes hydrolysis of β-D- glu ...
reporter gene to produce the plant. The actual gun that shot the gold beads and produced the genetic modifications is now owned by the Smithsonian museum in
Washington, DC ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan ...
. Every ''Roundup Ready soybean'' in the world has a relative which was genetically transformed at Agracetus. 80% of the world's soybeans are ''Roundup Ready''. Agracetus was founded in 1981 as
Cetus Corporation Cetus Corporation was one of the first biotechnology companies. It was established in Berkeley, California, in 1971, but conducted most of its operations in nearby Emeryville. Before merging with Chiron Corporation in 1991 (now a part of Novart ...
. Acquired by Monsanto in 1996, the research and development facility is located 8 miles (13 km) west of Madison in the city of
Middleton, Wisconsin Middleton is a city in Dane County, Wisconsin, United States, and a suburb of the state capital, Madison. Middleton's motto is "The Good Neighbor City." The population was 21,827 at the 2020 census. In 2007, Middleton was chosen as the best pl ...
, on . The site has of research space, of greenhouse space, about 75 employees, and ten laboratories. Output of genetically modified soy plants is many thousands of transformation events per year. Genetically modified cotton and genetically modified rice is also an important effort at Agracetus.


References

{{Monsanto Agronomy Genetic engineering and agriculture Monsanto