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Alfa Aesar, headquartered in Ward Hill,
Massachusetts Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut assachusett writing systems, məhswatʃəwiːsət'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England ...
,
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
, is a supplier of
reagent In chemistry, a reagent ( ) or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms ''reactant'' and ''reagent'' are often used interchangeably, but reactant specifies a ...
s and materials for use in
research and development Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existi ...
, and analysis. They have facilities in many countries and manufacture many of the chemicals they sell.


History

The current Alfa Aesar setup - part of the Johnson Matthey Fine Chemicals & Catalysts Division - comes from a series of company mergers: * Alfa Inorganics was founded in 1962 by
Alfred Bader Alfred Robert Bader, Commander of the Order of the British Empire, CBE (April 28, 1924 – December 23, 2018) was a Canadians, Canadian chemist, businessman, philanthropist, and collector of fine art. He was considered by the ''Chemical & Engine ...
, in a 50:50 venture between Aldrich Chemicals and Metal Hydrides Inc. The purpose was to provide a source of inorganic research chemicals to sit alongside the organic chemicals of Bader's other company: Aldrich Chemicals. It was created to market inorganics, organometallics, and others such as organoboron and organoarsenic reagents. Following the amalgamation of Aldrich and the Sigma Chemical Co, the joint venture was terminated with Alfa reverting to Metal Hydrides ownership (later Ventron, later again
Thiokol Thiokol (variously Thiokol Chemical Corporation(/Company), Morton Thiokol Inc., Cordant Technologies Inc., Thiokol Propulsion, AIC Group, ATK Thiokol, ATK Launch Systems Group; finally Orbital ATK before becoming part of Northrop Grumman) was an ...
). In the USA the business was branded as Alfa, and sold only inorganics. In Europe, the business was branded as Alfa-Ventron (to distinguish it from the UK company Alfa Chemicals) and also later sold a limited range of organic chemicals sourced from Lancaster Synthesis. The European sales office was in
Karlsruhe Karlsruhe ( , , ; South Franconian: ''Kallsruh'') is the third-largest city of the German state (''Land'') of Baden-Württemberg after its capital of Stuttgart and Mannheim, and the 22nd-largest city in the nation, with 308,436 inhabitants. ...
, Germany. The USA and European operations used different (though similar) catalogues, with completely different product number sequences and appear to have been run with a high degree of independence from each other. Thiokol eventually tired of the non-mainstream business and sold it to Aesar, who closed the USA site and relocated the business to the Aesar location. * Johnson Matthey Research Chemicals. Johnson-Matthey had two distinct research chemical catalogues, one of high purity inorganic chemicals and metals, the other a (short-lived) range of inorganic reagents, solvents and acids. This was operated from their facility at
Royston, Hertfordshire Royston is a town and Civil parishes in England, civil parish in the North Hertfordshire, District of North Hertfordshire and county of Hertfordshire in England. It is situated on the Prime meridian (Greenwich), Greenwich Meridian, which brush ...
U.K. Royston had manufacturing and machining equipment for high purity metal foils, powders, ribbons and salts. *
Aesar Alfa Aesar, headquartered in Ward Hill, Massachusetts, United States, is a supplier of reagents and materials for use in research and development, and analysis. They have facilities in many countries and manufacture many of the chemicals they sel ...
. This was Johnson Matthey's part-owned USA distribution agent for their range of high purity inorganics. Aesar had no manufacturing or bottling facilities, being simply a distribution centre. Following the takeover of Alfa, the combined business was rebranded Alfa-Aesar, rationalised on the Aesar location at Ward Hill, and Johnson-Matthey assumed full ownership. This grew in importance to lead the Johnson Matthey research chemical interests. *
Lancaster Synthesis Lancaster may refer to: Lands and titles *The County Palatine of Lancaster, a synonym for Lancashire *Duchy of Lancaster, one of only two British royal duchies *Duke of Lancaster *Earl of Lancaster *House of Lancaster, a British royal dynasty ...
, initially based in Lancaster and then
Morecambe Morecambe ( ) is a seaside town and civil parish in the City of Lancaster district in Lancashire, England. It is in Morecambe Bay on the Irish Sea. Name The first use of the name was by John Whitaker in his ''History of Manchester'' (1771), w ...
,
Lancashire Lancashire ( , ; abbreviated Lancs) is the name of a historic county, ceremonial county, and non-metropolitan county in North West England. The boundaries of these three areas differ significantly. The non-metropolitan county of Lancashi ...
UK. This business was founded by Eric Wildsmith and Wilf Maughan and specialised in the manufacture and supply of organic research chemicals. The business was sold to MTM PLC for £20,000,000 in 1989, following which Maughan retired and Wildsmith was eventually ousted as Managing Director by the Executive Chairman of MTM : Richard Lines. MTM subsequently went bankrupt, Lines and the MTM Financial Director, Tom Baxter were jailed for fraud, and Lancaster Synthesis (by then rebranded MTM Research Chemicals) was sold to BTP PLC in 1993 - who reverted the name to Lancaster Synthesis. BTP in turn was later sold to
Clariant Clariant AG is a Swiss multinational speciality chemicals company, formed in 1995 as a spin-off from Sandoz. The company is focused on four business areas: care chemicals (consumer and industrial); catalysis; natural resources (oil & mining, mine ...
, who had no idea what to do with a catalogue company - and eventually agreed a sale to Johnson Matthey for £14,000,000. Unfortunately a few weeks before the sale was due to complete, an unexplained major fire destroyed the scale-up plant and the majority of the bulk stock. This has echoes of another destructive fire on the eve of the MTM takeover, which totally destroyed a manufacturing laboratory. The Lancaster Synthesis sites have now all closed, with all UK operations moved to the newer Avocado facilities at Heysham. During the period of MTM ownership, a series of other companies were acquired and brought under notional control: Loba Feinchemie (Fischamend, Austria), Farchan Laboratories (
Gainesville, Florida Gainesville is the county seat of Alachua County, Florida, Alachua County, Florida, and the largest city in North Central Florida, with a population of 141,085 in 2020. It is the principal city of the Gainesville metropolitan area, Florida, Gaine ...
) Monomer Polymer & Dajac Labs (USA). These were all sold back to their previous owners or local management following the MTM collapse as they required too high a management input from the UK, and had never been properly integrated. Not long after Farchan was returned to local management it also was destroyed in a fire, subsequently relocating to Columbus, OH close to the location of its founding, where its initial technology had been based on research into high performance aviation fuels during WWII by Henry Channon. During the period of MTM ownership a short-lived distribution agreement existed for
Farmitalia-Carlo Erba Farmitalia was an Italian pharmaceutical company best known for its parallel discovery with Rhone-Poulenc of daunorubicin and subsequent discovery of doxorubicin. Farmitalia had been founded in 1935 as a joint venture by Rhone-Poulenc and Monte ...
to distribute Lancaster Synthesis products through a Carlo Erba rebranded version of the LS catalogue. However this venture was a failure and only lasted for one catalogue edition: the Italians proved unable to commit the required marketing resources to the project. *
Fairfield Chemicals Fairfield may refer to: Places Australia * Fairfield, New South Wales, a western suburb of Sydney. **Electoral district of Fairfield, the corresponding seat in the New South Wales Legislative Assembly * Fairfield, Queensland * Fairfield, Victori ...
,
Blythewood, South Carolina Blythewood is a town in Richland and Fairfield counties, South Carolina, United States. It is a suburb of Columbia, South Carolina. The 2020 United States census puts the population at 4,772, up from 2,034 in 2010. Since 2000, the population has ...
. This was a small-scale manufacturing plant near Columbia S.C. which specialised in hazardous chemistry, often involving fluorine and phosgene. It was acquired by MTM from its founder, Hiram S. Allen, as a USA manufacturing plant for Lancaster Synthesis, and was the one MTM Research Chemical acquisition that was properly integrated and managed. Like many other similar small chemical sites in that part of South Carolina, it was subject to intense local environmental concerns and pressures, driving Clariant to eventually close the site. However the intellectual property, stock and customers were transferred to Lancaster Synthesis prior to closure. *
Avocado Research Chemicals The avocado (''Persea americana'') is a medium-sized, evergreen tree in the laurel family (Lauraceae). It is native to the Americas and was first domesticated by Mesoamerican tribes more than 5,000 years ago. Then as now it was prized for i ...
, based in
Heysham Heysham ( ) is a coastal town in Lancashire, England, overlooking Morecambe Bay. It is a Heysham Port, ferry port, with services to the Isle of Man and Ireland, and the site of two Heysham nuclear power station, nuclear power stations. Demogra ...
,
Lancashire Lancashire ( , ; abbreviated Lancs) is the name of a historic county, ceremonial county, and non-metropolitan county in North West England. The boundaries of these three areas differ significantly. The non-metropolitan county of Lancashi ...
, UK, specializing in organic chemicals. This was Eric Wildsmiths second foray into the research chemical business. Originally based in Lancaster, it quickly grew, moving to a purpose built location at Heysham following a serious fire at its second location on Caton Road, Lancaster. It was subsequently sold to Johnson-Matthey for £25,000,000 and integrated into Alfa-Aesar, becoming their main organic production plant. Both Lancaster Synthesis and Avocado had close trading links to Alfa at various times prior to the takeover: the organic products sold in Germany through the Alfa-Ventron catalogue were sourced from Lancaster, while Avocado products were distributed both in the USA and Germany by the combined Alfa-Aesar. During the late 1970s / early 1980s, Lancaster Synthesis was the primary UK distribution agent for the USA Alfa range, taking this business over after it was relinquished by Aldrich UK. However this relationship was undermined when Alfa-Ventron independently opened its own short-lived sales unit in the Thiokol-Morton offices in Coventry. On June 25, 2015, Johnson Matthey agreed to sell Alfa Aesar for an amount of £256 million to Thermo Fisher Scientific. Johnson Mattey cited that "This is a further step in delivering our strategy to focus on areas where we can apply our expertise in complex chemistry". Thermo Fisher Scientific cited that "The acquisition of Alfa Aesar enhances our existing portfolio of chemicals, solvents and reagents to support virtually every laboratory application – from research, to drug discovery and development, to production, In addition, customers will benefit from greater access to these products through our extensive global commercial reach.". The acquirement was completed at the end of 2015. Johnson Matthey and Thermo Fisher Scientific both made statements, as well as Alfa Aesar.


Current Manufacturing

Their main manufacturing
organic chemical In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The st ...
facility is located at
Heysham Heysham ( ) is a coastal town in Lancashire, England, overlooking Morecambe Bay. It is a Heysham Port, ferry port, with services to the Isle of Man and Ireland, and the site of two Heysham nuclear power station, nuclear power stations. Demogra ...
, Lancashire, UK. . This has been supplemented by a bulk manufacturing site at
Yantai Yantai, Postal Map Romanization, formerly romanization of Chinese, known as Chefoo, is a coastal prefecture-level city on the Shandong Peninsula in northeastern Shandong province of People's Republic of China. Lying on the southern coast of ...
, China


Product lines

The company supplies a large variety of chemicals for various disciplines including: *
Organic chemistry Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; ...
*
Inorganic chemistry Inorganic chemistry deals with synthesis and behavior of inorganic and organometallic compounds. This field covers chemical compounds that are not carbon-based, which are the subjects of organic chemistry. The distinction between the two disci ...
* Analytical chemistry * Chromatography *
Semiconductor A semiconductor is a material which has an electrical resistivity and conductivity, electrical conductivity value falling between that of a electrical conductor, conductor, such as copper, and an insulator (electricity), insulator, such as glas ...
manufacturing *Pure
chemical element A chemical element is a species of atoms that have a given number of protons in their nuclei, including the pure substance consisting only of that species. Unlike chemical compounds, chemical elements cannot be broken down into simpler sub ...
s *
Biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
and
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
*Large scale chemicals &
contract manufacturing A contract manufacturer (CM) is a manufacturer that contracts with a firm for components or products (in which case it is a turnkey supplier). It is a form of outsourcing. A contract manufacturer performing packaging operations is called copacker o ...
Alfa Aesar is a major supplier in the research and fine chemicals market offering over 30,000 products - many of which are rare compounds, which are unique to a major catalogue supplier. Alfa Aesar provides materials for
drug discovery In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by ...
, materials science and all the essential building blocks for
organic synthesis Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one o ...
.


Notes and references


External links

{{Portal, Companies
Official websiteReport of LS sale to Johnson-MattheyAldrichima Acta edition which briefly mention origins of Alfa Inorganics
Research support companies Companies based in Essex County, Massachusetts