Adrenodoxin-NADP⁺ reductase (, ''

adrenodoxin reductase Adrenodoxin reductase (Enzyme Nomenclature name: adrenodoxin-NADP+ reductase, EC 1.18.1.6), was first isolated from bovine adrenal cortex where it functions as the first enzyme in the mitochondrial P450 systems that catalyze essential steps in s ...

'', ''nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase'', ''ADR'', ''NADPH:adrenal ferredoxin oxidoreductase'') is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

with

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...

''adrendoxin:NADP⁺ oxidoreductase''. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

: 2 reduced

adrenodoxin Adrenal ferredoxin (also adrenodoxin (ADX), adrenodoxin, mitochondrial, hepatoredoxin, ferredoxin-1 (FDX1)) is a protein that in humans is encoded by the ''FDX1'' gene. In addition to the expressed gene at this chromosomal locus (11q22), there a ...

+ NADP⁺

\rightleftharpoons

2 oxidized adrenodoxin + NADPH + H⁺ Adrenodoxin-NADP+ reductase is a

flavoprotein Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin. Flavoproteins are involved in a wide array of biological processes, including removal of radicals contributing to oxidative stress, photosynthesis, and DNA repair ...

(FAD).

References

External links

* {{Portal bar, Biology, border=no EC 1.18.1