Aceprometazine ( INN) is a phenothiazine derivative

prescription drug A prescription drug (also prescription medication or prescription medicine) is a pharmaceutical drug that legally requires a medical prescription to be dispensed. In contrast, over-the-counter drugs can be obtained without a prescription. The rea ...

with neuroleptic and

anti-histamine Antihistamines are pharmaceutical drug, drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, Generic drug, generic (not patented) drug that can be bought over ...

properties It is not widely prescribed, and may be associated with drug-induced Parkinsonism. It may be used in combination with meprobamate for the treatment of sleep disorders. This combination is available in France under the trade name Mepronizine. It is structurally related to the phenothiazine derivative veterinary drug '' acepromazine''.

Synthesis

The reason for the rearrangement in the sidechain between the precursor and the product is on account of a methadone-type

aziridine Aziridine is an organic compound consisting of the three-membered heterocycle . It is a colorless, toxic, volatile liquid that is of significant practical interest. Aziridine was discovered in 1888 by the chemist Siegmund Gabriel. Its derivati ...

2-Acetylphenothiazine 631-94-3(1) 2-Chloropropyldimethylamine 08-14-5(2)

References

D2 antagonists Phenothiazines H1 receptor antagonists Aromatic ketones {{nervous-system-drug-stub