Abediterol (

INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...

; development codes AZD-0548 and LAS 100977) is a once-daily experimental drug candidate for the treatment of

asthma Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, c ...

and

chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...

(COPD). It is currently under development by the Spanish pharmaceutical company Almirall and is in

Phase II Phase II, Phase 2 or Phase Two may refer to: Media * Marvel Cinematic Universe: Phase Two, six American superhero films from 2013–2015 * ''Star Trek: Phase II'', an unrealized television series based on the characters of Gene Roddenberry's ''S ...

clinical trials. It acts as a dual β₂ adrenergic agonist and

muscarinic antagonist A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor. The muscarinic receptor is a protein involved in the transmission of signals through certain parts of the ...

and is classified as an ultra-long-acting β₂ agonist (ultra-LABA). Its coformulation with mometasone furoate is also in Phase II clinical trials.

References

Long-acting beta2-adrenergic agonists Muscarinic antagonists Organofluorides 2-Quinolones Phenols Phenylethanolamines {{respiratory-system-drug-stub