Abediterol (

INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...

; development codes AZD-0548 and LAS 100977) is a once-daily experimental drug candidate for the treatment of

asthma Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, co ...

and

chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...

(COPD). It is currently under

development Development or developing may refer to: Arts *Development hell, when a project is stuck in development *Filmmaking, development phase, including finance and budgeting *Development (music), the process thematic material is reshaped * Photograph ...

by the Spanish pharmaceutical company

Almirall Almirall, S.A. is a Spanish pharmaceutical company, with headquarters in Barcelona, founded in 1943. In 2016, it generated total revenue of €859.3 million and became the leading pharmaceutical company in R&D investment in Spain. With over ...

and is in Phase II clinical trials. It acts as a dual β₂ adrenergic agonist and

muscarinic antagonist A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor. The muscarinic receptor is a protein involved in the transmission of signals through certain parts of the ...

and is classified as an ultra-long-acting β₂ agonist (ultra-LABA). Its coformulation with

mometasone furoate Mometasone, also known as mometasone y 3 s, is a steroid medication used to treat certain skin conditions, hay fever, and asthma. Specifically it is used to prevent rather than treat asthma attacks. It can be applied to the skin, inhaled, or use ...

is also in Phase II clinical trials.

References

Long-acting beta2-adrenergic agonists Muscarinic antagonists Organofluorides 2-Quinolones Phenols Phenylethanolamines {{respiratory-system-drug-stub