R05C Expectorants, excluding combinations with cough suppressants

R05CA Expectorants

:R05CA01

Tyloxapol Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through ...

:R05CA02 Potassium iodide :R05CA03

Guaifenesin Guaifenesin, also known as glyceryl guaiacolate, is an expectorant medication that aids in the elimination of sputum from the respiratory tract. Chemically it is an ether of guaiacol and glycerine. It is often used in combination with other me ...

:R05CA04 Ipecacuanha :R05CA05 Altheae radix :R05CA06 Senega :R05CA07 Antimony pentasulfide :R05CA08 Creosote :R05CA09 Guaiacolsulfonate :R05CA10 Combinations :R05CA11

Levoverbenone Levoverbenone is an expectorant. It is the L-isomer of verbenone Verbenone is a natural organic compound classified as a terpene that is found naturally in a variety of plants. The chemical has a pleasant characteristic odor. Besides being a ...

:R05CA12 Hederae helicis folium :R05CA13 Cineole

R05CB Mucolytics

:R05CB01

Acetylcysteine Acetylcysteine, also known as ''N''-acetylcysteine (NAC), is a medication that is used to treat paracetamol overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders like pneumonia and bronchitis. It has been used ...

:R05CB02

Bromhexine Bromhexine is a mucolytic drug used in the treatment of respiratory system, respiratory disorders associated with viscid or excessive mucus. It was developed in the research laboratory of Boehringer Ingelheim in the late 1950s as an active ingre ...

:R05CB03 Carbocisteine :R05CB04

Eprazinone Eprazinone (trade names Eftapan, Isilung, Mucitux) is a mucolytic and bronchospasm Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles. It is caused by the release (degranulation) of substan ...

:R05CB05 Mesna :R05CB06 Ambroxol :R05CB07 Sobrerol :R05CB08

Domiodol Domiodol is a mucolytic and expectorant Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expecto ...

:R05CB09

Letosteine Letosteine is a mucolytic patented (U.S. patent 6987120) by Piero del Soldato of Milan Milan ( , , Lombard: ; it, Milano ) is a city in northern Italy, capital of Lombardy, and the second-most populous city proper in Italy after Rome. ...

:R05CB10 Combinations :R05CB11

Stepronin Stepronin is a mucolytic and expectorant Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expector ...

:R05CB13 Dornase alfa (

desoxyribonuclease Deoxyribonuclease (DNase, for short) refers to a group of glycoprotein endonucleases which are enzymes that catalyze the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA. The role of the DNase enzyme in cells ...

) :R05CB14

Neltenexine Neltenexine (trade name Alveoten) is a mucolytic Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include ...

:R05CB15 Erdosteine :R05CB16 Mannitol :QR05CB90 Dembrexine hydrochloride

R05D
Cough suppressant Cold medicines are a group of medicinal, medications taken individually or in Combination drug, combination as a Symptomatic treatment, treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The t ...
s, excluding combinations with expectorants

R05DA Opium alkaloids and derivatives

:R05DA01

Ethylmorphine Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive. Side effects Adverse effects are similar to other opioids and include drowsiness, constipation, vertigo, nausea, vomiting, and respirat ...

:R05DA03 Hydrocodone :R05DA04

Codeine Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically use ...

:R05DA05 Opium alkaloids with morphine :R05DA06

Normethadone Normethadone (International Nonproprietary Name, INN, British Approved Name, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a Chemical synthesis, sy ...

:R05DA07 Noscapine :R05DA08

Pholcodine Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine. Pholcodine is ...

:R05DA09

Dextromethorphan Dextromethorphan (DXM) is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines. It is sold in syrup, tablet, spray, and lozenge forms. In 2022, the FDA approved a formulation of it combined with bu ...

:R05DA10

Thebacon Thebacon (INN; pronounced ), or dihydrocodeinone enol acetate, is a semisynthetic opioid that is similar to hydrocodone and is most commonly synthesised from thebaine. Thebacon was invented in Germany in 1924, four years after the first synthe ...

:R05DA11

Dimemorfan Dimemorfan (INN) (or dimemorphan) (brand names Astomin, Dastosirr, Tusben), or dimemorfan phosphate (JAN), also known as 3,17-dimethylmorphinan, is an antitussive (cough suppressant) of the morphinan family that is widely used in Japan and is als ...

:R05DA12

Acetyldihydrocodeine Acetyldihydrocodeine is an opiate derivative discovered in Germany in 1914 and was used as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Acetyldihydrocodeine is a very close relative deri ...

:R05DA20 Combinations ''(QR05DA20 Combinations of opium alkaloids and derivatives)'' :QR05DA90 Butorphanol

R05DB Other cough suppressants

:R05DB01 Benzonatate :R05DB02 Benproperine :R05DB03 Clobutinol :R05DB04 Isoaminile :R05DB05 Pentoxyverine :R05DB07

Oxolamine Oxolamine is a cough suppressant that is available as a generic drug in many jurisdictions. Oxolamine also has anti-inflammatory activity, which causes a reduction in irritation of the nerve receptors of the respiratory tract. It is mainly u ...

:R05DB09 Oxeladin :R05DB10 Clofedanol :R05DB11

Pipazetate Pipazetate () (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (), is a pyridobenzthiazine cough suppressant, closely related to the phenothiazine class. It binds to the sigma-1 receptor with an IC50 value of 190 nM. ...

:R05DB12 Bibenzonium bromide :R05DB13

Butamirate Butamirate (or brospamin, trade names Acodeen, Codesin, Pertix, Sinecod, Sinecoden, Sinecodix) is a cough suppressant. It has been marketed in Europe and Mexico, but not in the United States. As the citrate salt, it is sold in the form of lozenge ...

:R05DB14

Fedrilate Fedrilate is a centrally acting cough suppressant. It was patented as a mucolytic by UCB (company), UCB in 1971, but was never brought to market in the US. In the Netherlands, it has been marketed as Tussefan and in combination with guaifenesin a ...

:R05DB15 Zipeprol :R05DB16 Dibunate :R05DB17 Droxypropine :R05DB18 Prenoxdiazine :R05DB19 Dropropizine :R05DB20 Combinations :R05DB21

Cloperastine Cloperastine (INN) or cloperastin, in the forms of cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in ...

:R05DB22 Meprotixol :R05DB23

Piperidione Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione. It used to be marketed by Roche as a cough medicine available in liquid form. In the US, it was approved by the FDA on grounds of safety al ...

:R05DB24

Tipepidine Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate (JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class. It acts as an ...

:R05DB25 Morclofone :R05DB26 Nepinalone :R05DB27

Levodropropizine Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression whic ...

:R05DB28 Dimethoxanate :R05DB29

Gefapixant Gefapixant (MK-7264) is a drug which acts as an antagonist of the P2RX3 receptor, and may be useful in the treatment of chronic cough Chronic cough is long-term coughing, sometimes defined as more than several weeks or months. The term can be u ...

R05F Cough suppressants and expectorants, combinations

R05FA Opium derivatives and expectorants

:R05FA01 Opium derivatives and mucolytics :R05FA02 Opium derivatives and expectorants

R05FB Other cough suppressants and expectorants

:R05FB01 Cough suppressants and mucolytics :R05FB02 Cough suppressants and expectorants

R05X Other cold preparations

:''Empty group''

References

{{Cough and cold preparations R05