M05B Drugs affecting bone structure and mineralization

M05BA
Bisphosphonate Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. They are called bisphosphonates because they ...
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:M05BA01

Etidronic acid Etidronic acid, also known as etidronate, is a non-nitrogenous bisphosphonate used as a medication, detergent, water treatment, and cosmetic. It was patented in 1966 and approved for medical use in 1977. Use Medical Etidronic acid is a bisph ...

:M05BA02

Clodronic acid Clodronic acid ( INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce verteb ...

:M05BA03

Pamidronic acid Pamidronic acid or pamidronate disodium or APD (marketed as Aredia among others), is a nitrogen-containing bisphosphonate used to prevent osteoporosis. It was patented in 1971 and approved for medical use in 1987. Medical uses It is used to pr ...

:M05BA04

Alendronic acid Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. It is taken by mouth. Use is often recommended together with vitamin D, calcium supplementat ...

:M05BA05

Tiludronic acid Tiludronic acid ( INN; also known as tiludronate) is a bisphosphonate used for treatment of Paget's disease of bone (osteitis deformans) in human medicine. It has the tradename Skelid. In veterinary medicine, tiludronic acid is used to treat n ...

:M05BA06

Ibandronic acid Ibandronic acid is a bisphosphonate medication used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). ...

:M05BA07

Risedronic acid Risedronic acid, often used as its sodium salt risedronate sodium, is a bisphosphonate. It slows down the cells which break down bone. It's used to treat or prevent osteoporosis, and treat Paget's disease of bone. It is taken by mouth. It was pa ...

:M05BA08

Zoledronic acid Zoledronic acid, also known as zoledronate and sold under the brand name Zometa by Novartis among others, is a medication used to treat a number of bone diseases. These include osteoporosis, high blood calcium due to cancer, bone breakdown due ...

M05BB Bisphosphonates, combinations

:M05BB01 Etidronic acid and

calcium Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to ...

, sequential :M05BB02 Risedronic acid and calcium, sequential :M05BB03 Alendronic acid and colecalciferol :M05BB04 Risedronic acid, calcium and

colecalciferol Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D that is made by the skin when exposed to sunlight; it is found in some foods and can be taken as a dietary supplement. Cholecalciferol is made in the skin fo ...

, sequential :M05BB05 Alendronic acid, calcium and colecalciferol, sequential :M05BB06 Alendronic acid and

alfacalcidol Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive. Alfacalcidol has a weaker impact on calcium metabolism and parathyroid hormone levels than calcitriol, howev ...

, sequential :M05BB07 Risedronic acid and colecalciferol :M05BB08 Zoledronic acid, calcium and colecalciferol, sequential :M05BB09 Ibandronic acid and colecalciferol

M05BC
Bone morphogenetic protein Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of piv ...
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:M05BC01 Dibotermin alfa :M05BC02 Eptotermin alfa

M05BX Other drugs affecting bone structure and mineralization

:M05BX01 Ipriflavone :M05BX02

Aluminium chlorohydrate Aluminium chlorohydrate is a group of water-soluble, specific aluminium salts having the general formula Aln Cl(3n-m)( OH)m. It is used in cosmetics as an antiperspirant and as a coagulant in water purification. In water purification, this compou ...

:M05BX03

Strontium ranelate Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it bo ...

:M05BX04

Denosumab Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is contraindicated in people with low blood calci ...

:M05BX05

Burosumab Burosumab, sold under the brand name Crysvita, is a human monoclonal antibody medication approved 2018 for the treatment of X-linked hypophosphatemia and tumor-induced osteomalacia. Medical uses In the European Union and the United States, ...

:M05BX06

Romosozumab Romosozumab, sold under the brand name Evenity, is a medication used to treat osteoporosis. It has been found to decrease the risk of fractures of the spine. Common side effect include headache, joint pain, and pain at the site of injection. ...

:M05BX07

Vosoritide Vosoritide, sold under the brand name Voxzogo, is a medication used for the treatment of achondroplasia. The most common side effects include injection site reactions (such as swelling, redness, itching, or pain), vomiting, and decreased blood p ...

:M05BX08 Menatetrenone :M05BX53 Strontium ranelate and colecalciferol

References

{{Drugs for treatment of bone diseases M05