ADP-ribosylation factor 3 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''ARF3''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
Interactions
ARF3 has been shown to
interact
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with:
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ARFIP1
Arfaptin-1 is a protein that in humans is encoded by the ''ARFIP1'' gene.
Interactions
ARFIP1 has been shown to Protein-protein interaction, interact with ARF3.
References
Further reading
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External links
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{{gene-4-st ...
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* ARFIP2
Arfaptin-2 is a protein that in humans is encoded by the ''ARFIP2'' gene.
Interactions
ARFIP2 has been shown to interact with Arf6
ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding protei ...
,
* GGA1
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the ''GGA1'' gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family ar ...
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* ]GGA3
ADP-ribosylation factor-binding protein GGA3 is a protein that in humans is encoded by the ''GGA3'' gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous c ...
, and
* KIF23
Kinesin-like protein KIF23 is a protein that in humans is encoded by the ''KIF23'' gene.
Function
In cell division
KIF23 (also known as Kinesin-6, CHO1/MKLP1, C. elegans ZEN-4 and Drosophila Pavarotti) is a member of kinesin-like protein f ...
.
References
External links
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Further reading
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