350px, Actions of the major digestive hormones secreted by APUD cells
APUD cells (DNES cells) constitute a group of apparently unrelated
endocrine cells, which were named by the
scientist A.G.E. Pearse, who developed the APUD concept in the early 1960s. These cells share the common function of secreting a low molecular weight
polypeptide hormone. There are several different types which secrete the hormones
secretin
Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duode ...
,
cholecystokinin and several others. The name is derived from an
acronym, referring to the following:
[ ]
* Amine Precursor Uptake – for high uptake of amine precursors including 5-hydroxytryptophan (
5-HTP
5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
Uses
5-HTP is sold over the counter i ...
) and dihydroxyphenylalanine (
DOPA).
* Decarboxylase – for high content of the
enzyme amino acid decarboxylase (for conversion of precursors to amines).
Cells in APUD system
# ''Adenohypophysis''
# Neurons of ''Hypothalamus''
# C-cells of ''Thyroid''
# Chief Cells of ''Parathyroid''
# ''Adrenal Medullary'' Cells
# Glomus cells in ''Carotid Body''
# Melanocytes of ''Skin''
# Cells of ''Pineal Gland''
# Renin producing cells in ''Kidney''
See also
*
Apudoma
*
Enteroendocrine cell
*
Neuroendocrine cell
*
List of human cell types derived from the germ layers
This is a list of cells in humans derived from the three embryonic germ layers – ectoderm, mesoderm, and endoderm.
Cells derived from ectoderm
Surface ectoderm Skin
* Trichocyte
* Keratinocyte
Anterior pituitary
* Gonadotrope
* Corticotro ...
References
External links
*
Endocrine cells
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