Aldehyde dehydrogenase 8 family, member A1 also known as ALDH8A1 is an
enzyme that in humans is encoded by the ''ALDH8A1''
gene.
Function
This protein belongs to the
aldehyde dehydrogenase family of enzymes. It was originally thought to play a role in a pathway of 9-cis-
retinoic acid biosynthesis
Biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined to form macromolecules. ...
in vivo. However, bioinformatics and experimental work has shown that it is more likely the aldehyde dehydrogenase of the
kynurenine pathway, oxidizing 2-aminomuconate semialdehyde to 2-aminomuconic acid.
Two transcript variants encoding distinct isoforms have been identified for this gene.
References
External links
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{{gene-6-stub