ADP-glyceromanno-heptose 6-epimerase

In enzymology, an ADP-L-glycero-D-manno-heptose 6-epimerase () is an enzyme that catalysis, catalyzes the chemical reaction

:ADP-D-glycero-D-manno-heptose $\rightleftharpoons$ ADP-L-glycero-D-manno-heptose

Hence, this enzyme has one substrate (biochemistry), substrate, ADP-D-glycero-D-manno-heptose, and one product (chemistry), product, ADP-L-glycero-D-manno-heptose.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The List of enzymes, systematic name of this enzyme class is ADP-L-glycero-D-manno-heptose 6-epimerase. This enzyme participates in lipopolysaccharide biosynthesis. It employs one cofactor (biochemistry), cofactor, NADP+ in a direct oxidation mechanism.

Structural studies

As of 2007, only one tertiary structure, structure has been solved for this class of enzymes, with the Protein Data Bank, PDB accession code .

References

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EC 5.1.3
NADH-dependent enzymes
Enzymes of known structure

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