A643 may refer to:
*
A643 road
The A643 is a main road between Leeds and Huddersfield in West Yorkshire, England.
Its eastern end is at the Armley Gyratory roundabout on the western edge of Leeds City Centre. The road then goes through:
* Beeston
* Churwell
* Morley
* Br ...
, a road in England
*
Bundesautobahn 643
is a short autobahn in Germany. The motorway crosses the Rhine River, connecting the cities of Wiesbaden and Mainz, the capital cities of the German states of Hesse and Rhineland-Palatinate, respectively. It is one of two autobahns in Germany t ...
, a road in Germany
{{Disambiguation, letter number, road