The Actinobacterial 1 TMS Holin (A-1 Holin) Family (TC# 1.E.32) consists of proteins found in
actinobacteria
The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to so ...
, their conjugative plasmids and their phage. They are usually between 90 and 140 amino acyl residues (aas) in length and exhibit 1 or sometimes even 2 transmembrane segments despite the families name (i.e., TC# 1.E.32.2.1). Although some are annotated as
phage proteins or holins, members of the A-1 family are not yet functionally characterized. A representative list of proteins belonging to the A-1 Holin family can be found in the Transporter Classification Database (TCDB).
See also
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Holin
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Lysin
Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target ...
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Transporter Classification Database
Further reading
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References
{{CCBYSASource, sourcepath=http://tcdb.org/search/result.php?tc=1.E.32, sourcearticle=1.E.32 Actinobacterial 1 TMS Holin (A-1 Holin) Family, revision=699838558
Protein families
Membrane proteins
Transmembrane proteins
Transmembrane transporters
Transport proteins
Integral membrane proteins
Holins