8-Bromoadenosine 3',5'-cyclic adenosine monophosphate (8-Br-cAMP) is a
brominated derivative of
cyclic adenosine monophosphate (cAMP). 8-Br-cAMP is an activator of
cyclic AMP-dependent protein kinase
In cell biology, protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (). PKA has several functions in the cell, including regulatio ...
, and it is long-acting because it is resistant to degradation by
cyclic AMP phosphodiesterase.
8-Bromo Cyclic Adenosine Monophosphate
at PubChem
PubChem is a database of chemical molecules and their activities against biological assays. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of ...
See also
* 8-Bromoguanosine 3',5'-cyclic monophosphate
8-Bromoguanosine 3′,5′-cyclic monophosphate is a brominated derivative of cyclic guanosine monophosphate
Cyclic guanosine monophosphate (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP). cGMP acts as a second messenger ...
(8-Br-cGMP)
References
{{DEFAULTSORT:Bromoadenosine 3',5'-cyclic monophosphate, 8-
Nucleotides
Organobromides
Purines
Oxygen heterocycles
Phosphorus heterocycles