The 5-HT
2 receptors are a subfamily of
5-HT receptors that bind the
endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
The 5-HT
2 subfamily consists of three
G protein-coupled receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related p ...
s (GPCRs) which are coupled to
Gq/G11 and mediate
excitatory
In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential, caused by the ...
neurotransmission
Neurotransmission (Latin: ''transmissio'' "passage, crossing" from ''transmittere'' "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), ...
,
including
5-HT2A,
5-HT2B, and
5-HT2C. For more information, please see the respective main articles of the individual subtypes:
*
5-HT2A receptor
*
5-HT2B receptor
*
5-HT2C receptor
See also
*
5-HT1 receptor
*
5-HT3 receptor
*
5-HT4 receptor
*
5-HT5 receptor
*
5-HT6 receptor
*
5-HT7 receptor
*
5-HT2 antagonists
References
{{Serotonergics
Serotonin receptors