2,5-Dimethoxy-4-ethylthio-α-ethylphenethylamine (4C-T-2) is a
synthetic drug of the
phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amin ...
chemical class Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties. Whereas the structural properties are largely intrinsic, functional properties and the derived classificat ...
. It is the
α-
ethylated analogue of
2C-T-2
2C-T-2 is a psychedelic and entactogenic phenethylamine of the 2C family. It was first synthesized in 1981 by Alexander Shulgin, and rated by him as one of the "magical half-dozen" most important psychedelic phenethylamine compounds. The drug ...
.
Pharmacology
Binding profile
4C-T-2 has
affinity
Affinity may refer to:
Commerce, finance and law
* Affinity (law), kinship by marriage
* Affinity analysis, a market research and business management technique
* Affinity Credit Union, a Saskatchewan-based credit union
* Affinity Equity Partn ...
(K
i) for the
5-HT1A (5,339 nM),
5-HT1E (9,879 nM),
5-HT2A (274.1 nM),
5-HT2B (58.1 nM),
5-HT2C (468.6 nM),
5-HT5A (1,587 nM),
5-HT7 (3,829),
D3 (1,273 nM),
β2-adrenergic (124.9 nM),
I1 (946.5 nM), and
σ1 (514 nM)
receptor
Receptor may refer to:
* Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ...
s.
The
activity of 4C-T-2 at these sites has not been assayed, with the exception of the 5-HT
2A and 5-HT
2C receptors where it acts as a
partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist. They may also be considered ligands which display both agonistic and antagonistic e ...
.
See also
*
2C-T-2
2C-T-2 is a psychedelic and entactogenic phenethylamine of the 2C family. It was first synthesized in 1981 by Alexander Shulgin, and rated by him as one of the "magical half-dozen" most important psychedelic phenethylamine compounds. The drug ...
*
4C-B
*
Aleph-7
*
Ariadne
Ariadne (; grc-gre, Ἀριάδνη; la, Ariadne) was a Cretan princess in Greek mythology. She was mostly associated with mazes and labyrinths because of her involvement in the myths of the Minotaur and Theseus. She is best known for having ...
References
Phenethylamines
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