4-Thiouracil
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4-Thiouracil is a heterocyclic organic compound having a
pyrimidine Pyrimidine (; ) is an aromatic, heterocyclic, organic compound similar to pyridine (). One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has nitrogen atoms at positions 1 and 3 in the ring. The other ...
skeleton. It is a derivative of the nucleobase
uracil Uracil () (symbol U or Ura) is one of the four nucleobases in the nucleic acid RNA. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil nucleobase is replaced by ...
with a sulfur instead of oxygen in position 4. It is found naturally in the
4-thiouridine 4-Thiouridine is an atypical nucleotide Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) ...
nucleotide.


References

Pyrimidines Thioureas Nucleobases {{heterocyclic-stub