4,4′-Biphenol is an
organic compound
In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The ...
which is a
phenol
Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it req ...
ic derivative of
biphenyl
Biphenyl (also known as diphenyl, phenylbenzene, 1,1′-biphenyl, lemonene or BP) is an organic compound that forms colorless crystals. Particularly in older literature, compounds containing the functional group consisting of biphenyl less one ...
. It is a colorless solid.
4,4′-Biphenol is prepared by dealkylation of the tetra-''t''-butyl derivative, generated by the oxidative coupling of
2,6-di-''tert''-butylphenol. The
oxidative coupling Oxidative coupling in chemistry is a coupling reaction of two molecular entities through an oxidative process. Usually oxidative couplings are catalysed by a transition metal complex like in classical cross-coupling reactions, although the underly ...
of phenol itself typically gives a mixture of isomers.
For example,
VCl4 reacts with phenols give 4,4′-, 2,4′-, and 2,2′-
biphenol
In organic chemistry, a biphenol refers to compounds with the formula (C6H4OH)2. Such compounds formally result from the coupling of two phenols.
{{short description, Chemical compound
Three symmetrical isomer
In chemistry, isomers are mol ...
s:
:2 C
6H
5OH + 2 VCl
4 → HOC
6H
4–C
6H
4OH + 2 VCl
3 + 2 HCl
An earlier process using oxygen and copper salts to enable the oxidative coupling was reported
Safety
4,4'-Biphenol had actually been elucidated to have an œstrogenic SAR.
See Also
*
Bisphenol
The bisphenols () are a group of chemical compounds related to diphenylmethane. Most are based on two hydroxyphenyl functional groups linked by a methylene bridge. Exceptions include bisphenol S, P, and M. "Bisphenol" is a common name; the letter ...
References
{{DEFAULTSORT:Biphenol, 4, 4'-
Phenols
Biphenyls