Acacetin is a 4′- ''O''-methylated flavone of the parent compound apigenin, found in ''

Robinia pseudoacacia ''Robinia pseudoacacia'', commonly known in its native territory as black locust, is a medium-sized hardwood deciduous tree, belonging to the tribe Robinieae of the legume family Fabaceae. It is endemic to a few small areas of the United States, ...

'' (black locust), ''

Turnera diffusa ''Turnera diffusa'', known as damiana, is a shrub native to southern Texas in the United States, Central America, Mexico, South America, and the Caribbean. It belongs to the family Passifloraceae. Damiana is a relatively small, woody shrub tha ...

'' (damiana), shows moderate aromatase inhibition, '' Betula pendula'' (silver birch), and in the fern ''

Asplenium normale ''Asplenium'' is a genus of about 700 species of ferns, often treated as the only genus in the family Aspleniaceae, though other authors consider '' Hymenasplenium'' separate, based on molecular phylogenetic analysis of DNA sequences, a different ...

''. In plant synthesis the enzyme apigenin 4′-''O''-methyltransferase uses ''S''-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce ''S''-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin).

References

Aromatase inhibitors O-methylated flavones {{aromatic-stub

See also

References