3-Nitrooxypropanol, abbreviated 3NOP, is an

organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The ...

with the formula HOCH₂CH₂CH₂ONO₂. It is the mono

nitrate ester In organic chemistry, a nitrate ester is an organic functional group with the formula , where R stands for any organic residue. They are the esters of nitric acid and alcohols. A well-known example is nitroglycerin, which is not a ''nitro'' co ...

of 1,3-propanediol. The compound is an inhibitor of the enzyme

methyl coenzyme M reductase In enzymology, coenzyme-B sulfoethylthiotransferase, also known as methyl-coenzyme M reductase (MCR) or most systematically as 2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase is an enzyme that ...

(MCR). MCR catalyzes the final step in

methanogenesis Methanogenesis or biomethanation is the formation of methane coupled to energy conservation by microbes known as methanogens. Organisms capable of producing methane for energy conservation have been identified only from the domain Archaea, a group ...

. When it is fed to

ruminant Ruminants (suborder Ruminantia) are ungulate, hoofed herbivorous grazing or browsing mammals that are able to acquire nutrients from plant-based food by Enteric fermentation, fermenting it in a specialized stomach prior to digestion, principally ...

s, their methane production is diminished. In 2021 Bovaer, a feed additive for cows produced by

DSM DSM or dsm may refer to: Science and technology * Deep space maneuver * Design structure matrix or dependency structure matrix, a representation of a system or project * Diagnostic and Statistical Manual of Mental Disorders ** DSM-5, the fifth ed ...

based on this compound, has been approved in Brazil, one of the world's largest meat exporters and also Chile. In 2022, it was approved for use on dairy cows in the EU.

References

{{DEFAULTSORT:Nitrooxypropanol, 3- Enzyme inhibitors Nitrate esters Anaerobic digestion Biodegradable waste management Animal feed

See also

References