3,5,7-Trioxododecanoyl-CoA Synthase
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3,5,7-Trioxododecanoyl-CoA synthase (, ''TKS'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with systematic name ''malonyl-CoA:hexanoyl-CoA malonyltransferase (3,5,7-trioxododecanoyl-CoA-forming)''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: 3
malonyl-CoA Malonyl-CoA is a coenzyme A derivative of malonic acid. Functions It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis. Fatty acid biosynthesis Malonyl-CoA provides 2-carbon units to fatty acids and commi ...
+ hexanoyl-CoA \rightleftharpoons 3 CoA + 3,5,7-trioxododecanoyl-CoA + 3 CO2 This polyketide synthase catalyse the first step in the cannabinoids biosynthetic pathway of the plant '' Cannabis sativa''.


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