3,4-dihydroxyphenylalanine Reductive Deaminase

The enzyme 3,4-dihydroxyphenylalanine reductive deaminase (EC 4.3.1.22, reductive deaminase, DOPA-reductive deaminase, DOPARDA; systematic name 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming)) catalyses the following chemical reaction

: L-dopa + 2 NADH $\rightleftharpoons$ 3,4-dihydroxyphenylpropanoate + 2 NAD⁺ + NH₃

This enzyme participates in L-phenylalanine catabolism in the anaerobic phototrophic bacterium '' Rhodobacter sphaeroides'' OU5.

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EC 4.3.1