The enzyme 3′(2′),5′-bisphosphate nucleotidase (EC 3.1.3.7)
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycl ...
the reaction
:adenosine 3′,5′-bisphosphate + H
2O
AMP + phosphate
This enzyme belongs to the family of
hydrolase
Hydrolase is a class of enzyme that commonly perform as biochemical catalysts that use water to break a chemical bond, which typically results in dividing a larger molecule into smaller molecules. Some common examples of hydrolase enzymes are es ...
s, specifically those acting on phosphoric
monoester
In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides ...
bonds. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
is adenosine-3′(2′),5′-bisphosphate 3′(2′)-phosphohydrolase. Other names in common use include phosphoadenylate 3′-nucleotidase, 3′-phosphoadenylylsulfate 3′-phosphatase, and 3′(2′),5′-bisphosphonucleoside 3′(2′)-phosphohydrolase. This enzyme participates in
sulfur metabolism
Sulfur is metabolized by all organisms, from bacteria and archaea to plants and animals. Sulfur is reduced or oxidized by organisms in a variety of forms. The element is present in proteins, sulfate esters of polysaccharides, steroids, pheno ...
.
Structural studies
As of late 2007, 6
structures
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such a ...
have been solved for this class of enzymes, with
PDB PDB may refer to:
* Chess Problem Database Server (PDB Server)
* 1,4-Dichlorobenzene (paradichlorobenzene)
* Party of German-speaking Belgians, (German: '), a political party and predecessor of the ProDG
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accession codes , , , , , and .
References
*
*
*
*
EC 3.1.3
Enzymes of known structure
{{3.1-enzyme-stub