2000 Simpsonwood CDC conference
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The 2000 Simpsonwood CDC conference (officially titled Scientific Review of Vaccine Safety Datalink Information) was a two-day meeting convened in June 2000 by the
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georg ...
(CDC), held at the Simpsonwood Methodist retreat and conference center in
Norcross, Georgia Norcross is a city in Gwinnett County, Georgia, United States. The population as of the 2010 census was 9,116, while in 2020 the population was 17,209. It is included in the Atlanta-Sandy Springs-Marietta metropolitan statistical area. History ...
. The key event at the conference was the presentation of data from the
Vaccine Safety Datalink The Vaccine Safety Datalink Project (VSD) was established in 1990 by the United States Centers for Disease Control and Prevention (CDC) to study the adverse effects of vaccines. Four large health maintenance organizations, including Kaiser Perman ...
examining the possibility of a link between the mercury compound thimerosol in vaccines and neurological problems in children who had received those vaccines. A 2005 article by
Robert F. Kennedy, Jr. Robert Francis Kennedy Jr. (born January 17, 1954) is an American environmental lawyer and author known for promoting anti-vaccine propaganda and conspiracy theories. Kennedy is a son of U.S. senator Robert F. Kennedy and a nephew of President ...
, published by ''
Rolling Stone ''Rolling Stone'' is an American monthly magazine that focuses on music, politics, and popular culture. It was founded in San Francisco, California, in 1967 by Jann Wenner, and the music critic Ralph J. Gleason. It was first known for its ...
'' and
Salon.com ''Salon'' is an American politically progressive/ liberal news and opinion website created in 1995. It publishes articles on U.S. politics, culture, and current events. Content and coverage ''Salon'' covers a variety of topics, including re ...
, focused on the Simpsonwood meeting as part of a conspiracy to withhold or falsify vaccine-safety information. However, Kennedy's article contained numerous major factual errors and, after a number of corrections, was ultimately retracted by Salon.com. Nonetheless, on the basis of Kennedy's claims, the conference gained notoriety in the anti-vaccination movement.


The conference

The conference was convened following a resolution by the
Congress of the United States The United States Congress is the legislature of the federal government of the United States. It is bicameral, composed of a lower body, the House of Representatives, and an upper body, the Senate. It meets in the U.S. Capitol in Wash ...
in 1997 requiring the
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
(FDA) to review the
thimerosal Thiomersal (INN), or thimerosal (USAN, JAN), is an organomercury compound. It is a well-established antiseptic and antifungal agent. The pharmaceutical corporation Eli Lilly and Company gave thiomersal the trade name Merthiolate. It has been us ...
content of approved drugs and biologics. Three vaccines of primary interest were discussed:
hepatitis B vaccine Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and t ...
,
DPT vaccine The DPT vaccine or DTP vaccine is a class of combination vaccines against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus. The vaccine components include diphtheria and tetanus toxoids and either kil ...
, and the
Hib vaccine The ''Haemophilus influenzae'' type B vaccine, also known as Hib vaccine, is a vaccine used to prevent ''Haemophilus influenzae'' type b (Hib) infection. In countries that include it as a vaccination schedule, routine vaccine, rates of severe ...
. Attendees included experts in the fields of
autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...
, pediatrics, toxicology, epidemiology and vaccines. Also in attendance were approximately half a dozen public-health organisations and pharmaceutical companies, as well as eleven consultants to the CDC, a
rapporteur A rapporteur is a person who is appointed by an organization to report on the proceedings of its meetings. The term is a French-derived word. For example, Dick Marty was appointed ''rapporteur'' by the Parliamentary Assembly of the Council of Eur ...
, and a statistician. The meeting served as a prelude to vaccine policy meetings held by the
Advisory Committee on Immunization Practices The Advisory Committee on Immunization Practices (ACIP) is a committee within the United States Centers for Disease Control and Prevention (CDC) that provides advice and guidance on effective control of vaccine-preventable diseases in the U.S. c ...
(ACIP), which sets U.S. vaccine policy for the CDC. The session was also to serve as the initial meeting of the ACIP work group on thimerosal and
immunization Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body, called ''non-s ...
. Presentations and supporting documents from the conference were subject to a
news embargo In journalism and public relations, a news embargo or press embargo is a request or requirement by a source that the information or news provided by that source not be published until a certain date or certain conditions have been met. They are of ...
until June 21, 2000, at which point they were published by the ACIP. Transcript: pp. 256–257 After the conference, researchers carried out a planned second phase to further analyze and clarify the study's preliminary findings. The results of this second analysis were published in 2003.


In the anti-vaccination movement

The June 20, 2005, issue of ''
Rolling Stone ''Rolling Stone'' is an American monthly magazine that focuses on music, politics, and popular culture. It was founded in San Francisco, California, in 1967 by Jann Wenner, and the music critic Ralph J. Gleason. It was first known for its ...
'' contained an article written by
Robert F. Kennedy, Jr. Robert Francis Kennedy Jr. (born January 17, 1954) is an American environmental lawyer and author known for promoting anti-vaccine propaganda and conspiracy theories. Kennedy is a son of U.S. senator Robert F. Kennedy and a nephew of President ...
, entitled "
Deadly Immunity "Deadly Immunity" is an article written by Robert F. Kennedy, Jr. that appeared in the July 14, 2005 issue of ''Rolling Stone'' and, simultaneously, on the website ''Salon''. The article is focused on the 2000 Simpsonwood CDC conference and cl ...
". The article, which was also published on
Salon.com ''Salon'' is an American politically progressive/ liberal news and opinion website created in 1995. It publishes articles on U.S. politics, culture, and current events. Content and coverage ''Salon'' covers a variety of topics, including re ...
, focused on the Simpsonwood conference, and alleged that government and private industry had colluded to "thwart the Freedom of Information Act" and "withhold" vaccine-safety findings from the public. Kennedy said that the Simpsonwood data linked thimerosal in vaccines to the rise in autism, but that the lead researcher later "reworked his data to bury the link between thimerosal and autism." However, Kennedy's article contained numerous errors, including overstating the amount of
ethylmercury Ethylmercury (sometimes ethyl mercury) is a cation composed of an organic CH3CH2- species (an ethyl group) bound to a mercury(II) centre, making it a type of organometallic cation, and giving it a chemical formula C2H5Hg+. The main source of et ...
in vaccines, wrongly claiming that a researcher held a patent on one of the discussed vaccines, and erroneously claiming that the
rotavirus vaccine Rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children. The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of ...
contained thimerosal. Salon.com later said that the errors in the article "went far in undermining Kennedy’s exposé", and corrected it on five occasions. The publisher later retracted it in January 2011, stating that criticisms of the article and flaws in the science connecting autism and vaccines undermined its value. By the time the final study results discussed at Simpsonwood were published in 2003, the lead researcher, Thomas Verstraeten, had gone to work for
GlaxoSmithKline GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tent ...
. Kennedy contended that the delay in publication gave Verstraeten sufficient time to fix the data around the CDC's alleged objective of obscuring a link between thimerosal and autism. Verstraeten denied the allegations, and published an account of the matter in the journal ''
Pediatrics Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
''. In September 2007, the U.S. Senate Committee on Health, Education, Labor and Pensions rejected allegations of impropriety against Verstraeten and the CDC. Addressing Kennedy's statements, the Committee found that: "Instead of hiding the impsonwooddata or restricting access to it, CDC distributed it, often to individuals who had never seen it before, and solicited outside opinion regarding how to interpret it. The transcript of these discussions was made available to the public."


See also

* Thiomersal and vaccines


Notes


References

* * Hosted by SafeMinds, {{DEFAULTSORT:Simpsonwood Cdc Conference Simpsonwood CDC conference, 2000 Simpsonwood CDC conference, 2000 Centers for Disease Control and Prevention Conspiracy theories in the United States 2000 conferences Thiomersal and vaccines 2000 in Georgia (U.S. state)