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23S rRNA (guanine2445-N2)-methyltransferase (, ''ycbY (gene)'', ''rlmL (gene)'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
''S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
S-adenosyl-L-methionine ''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur through ...
+
guanine Guanine () ( symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called ...
2445 in 23S rRNA \rightleftharpoons S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA The enzyme methylates
23S rRNA 3S may refer to: * 3S, for single, seventies/1970s, stuck, a slang form of sheng nu, a derogatory Chinese term referring to unmarried women in their mid to late twenties * 3S gondola lift * 3-S treatment, a method for dealing with unwanted or unwelc ...
in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...
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References


External links

* {{Portal bar, Biology, border=no EC 2.1.1