2,5-Dimethoxy-4-fluoroamphetamine (DOF) is a

psychedelic Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of ...

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...

of the

phenethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amin ...

and

amphetamine Amphetamine (contracted from alpha- methylphenethylamine) is a strong central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. It is also commonly used ...

classes.

Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamph ...

briefly describes DOF in his book '' PiHKAL'': DOF showed some stimulating effects in humans, but no psychedelic activity, after three doses of 6 mg spaced by one hour. Daniel Trachsel further suspected that the molar refraction of the important 4-substituent in DOF and 2C-F may be too low to activate the 5-HT_2A receptor sufficiently. DOF more closely mimics the effects of the 4-unsubstituted 2,5-dimethoxyamphetamine than the effects of

DOC DOC, Doc, doc or DoC may refer to: In film and television * ''Doc'' (2001 TV series), a 2001–2004 PAX series * ''Doc'' (1975 TV series), a 1975–1976 CBS sitcom * "D.O.C." (''Lost''), a television episode * ''Doc'' (film), a 1971 Wester ...

, DOB, and DOI.

References

{{DEFAULTSORT:Dimethoxy-4-fluoroamphetamine, 2, 5- Substituted amphetamines Serotonin receptor agonists Fluoroarenes 2,5-Dimethoxyphenethylamines

See also

References