1846–1860 cholera pandemic
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The third cholera pandemic (1846–1860) was the third major outbreak of cholera originating in India in the nineteenth century that reached far beyond its borders, which researchers at
UCLA The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California St ...
believe may have started as early as 1837 and lasted until 1863. In the
Russian Empire The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. ...
, more than one million people died of
cholera Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and ...
. In 1853–54, the epidemic in London claimed over 10,000 lives, and there were 23,000 deaths for all of
Great Britain Great Britain is an island in the North Atlantic Ocean off the northwest coast of continental Europe. With an area of , it is the largest of the British Isles, the largest European island and the ninth-largest island in the world. It is ...
. This pandemic was considered to have the highest fatalities of the 19th-century epidemics. It had high fatalities among populations in Asia, Europe, Africa and North America. In 1854, which was considered the worst year, 23,000 people died in Great Britain. That year, the British physician
John Snow John Snow (15 March 1813 – 16 June 1858) was an English physician and a leader in the development of anaesthesia and medical hygiene. He is considered one of the founders of modern epidemiology, in part because of his work in tracing the so ...
, who was working in a poor area of London, identified contaminated water as the means of
transmission Transmission may refer to: Medicine, science and technology * Power transmission ** Electric power transmission ** Propulsion transmission, technology allowing controlled application of power *** Automatic transmission *** Manual transmission *** ...
of the disease. After the
1854 Broad Street cholera outbreak Events January–March * January 4 – The McDonald Islands are discovered by Captain William McDonald aboard the ''Samarang''. * January 6 – The fictional detective Sherlock Holmes is perhaps born. * January 9 – The ...
he had mapped the cases of cholera in the
Soho Soho is an area of the City of Westminster, part of the West End of London. Originally a fashionable district for the aristocracy, it has been one of the main entertainment districts in the capital since the 19th century. The area was develop ...
area in London, and noted a cluster of cases near a water pump in one neighborhood. To test his theory, he convinced officials to remove the pump handle, and the number of cholera cases in the area immediately declined. His breakthrough helped eventually bring the epidemic under control. Snow was a founding member of the
Epidemiological Society of London The Epidemiological Society of London, also known as the Royal Society of Medicine's Epidemiological Society, was founded in London in 1850 with the objective of investigating the causes and conditions which influence the origin, propagation, m ...
, formed in response to a cholera outbreak in 1849, and he is considered one of the fathers of
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
.


Second pandemic

The second cholera pandemic spread from India, surging outward to all of Europe and northern Africa, then crossing the Atlantic to Canada and the United States, spreading to Mexico and the Caribbean. Many sources differ regarding when the second pandemic ended, and the third pandemic began. There are sources that maintain that the third cholera pandemic started with a surge from Bengal in 1839.


1840s

Over 15,000 people died of cholera in
Mecca Mecca (; officially Makkah al-Mukarramah, commonly shortened to Makkah ()) is a city and administrative center of the Mecca Province of Saudi Arabia, and the Holiest sites in Islam, holiest city in Islam. It is inland from Jeddah on the Red ...
in 1846.Asiatic Cholera Pandemic of 1846-63
UCLA School of Public Health.
In
Russia Russia (, , ), or the Russian Federation, is a List of transcontinental countries, transcontinental country spanning Eastern Europe and North Asia, Northern Asia. It is the List of countries and dependencies by area, largest country in the ...
, between 1847 and 1851, more than one million people died in the country's epidemic. A two-year outbreak began in
England and Wales England and Wales () is one of the three legal jurisdictions of the United Kingdom. It covers the constituent countries England and Wales and was formed by the Laws in Wales Acts 1535 and 1542. The substantive law of the jurisdiction is Eng ...
in 1848, and claimed 52,000 lives. In London, it was the worst outbreak in the city's history, claiming 14,137 lives, over twice as many as the 1832 outbreak. Cholera hit
Ireland Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in the Atlantic Ocean, North Atlantic Ocean, in Northwestern Europe, north-western Europe. It is separated from Great Britain to its east by the North Channel (Grea ...
in 1849 and killed many of the
Irish Famine The Great Famine ( ga, an Gorta Mór ), also known within Ireland as the Great Hunger or simply the Famine and outside Ireland as the Irish Potato Famine, was a period of starvation and disease in Ireland from 1845 to 1852 that constituted a h ...
survivors, already weakened by starvation and fever. In 1849, cholera claimed 5,308 lives in the major port city of
Liverpool Liverpool is a city and metropolitan borough in Merseyside, England. With a population of in 2019, it is the 10th largest English district by population and its metropolitan area is the fifth largest in the United Kingdom, with a popul ...
,
England England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe b ...
, an embarkation point for immigrants to North America, and 1,834 in Hull, England. In 1849, a second major outbreak occurred in Paris. Cholera, believed spread from Irish immigrant ship(s) from England to the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
, spread throughout the
Mississippi river system The Mississippi River System, also referred to as the Western Rivers, is a mostly riverine network of the United States which includes the Mississippi River and connecting waterways. The Mississippi River is the largest drainage basin in the Unit ...
, killing over 4,500 in
St. Louis St. Louis () is the second-largest city in Missouri, United States. It sits near the confluence of the Mississippi and the Missouri Rivers. In 2020, the city proper had a population of 301,578, while the bi-state metropolitan area, which e ...
and over 3,000 in
New Orleans New Orleans ( , ,New Orleans
Merriam-Webster.
; french: La Nouvelle-Orléans , es, Nuev ...
. Thousands died in
New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...
, a major destination for Irish immigrants. The outbreak that struck Nashville in 1849–1850 took the life of former U.S. President
James K. Polk James Knox Polk (November 2, 1795 – June 15, 1849) was the 11th president of the United States, serving from 1845 to 1849. He previously was the 13th speaker of the House of Representatives (1835–1839) and ninth governor of Tennessee (183 ...
. During the
California Gold Rush The California Gold Rush (1848–1855) was a gold rush that began on January 24, 1848, when gold was found by James W. Marshall at Sutter's Mill in Coloma, California. The news of gold brought approximately 300,000 people to California fro ...
, cholera was transmitted along the
California California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territori ...
,
Mormon Mormons are a religious and cultural group related to Mormonism, the principal branch of the Latter Day Saint movement started by Joseph Smith in upstate New York during the 1820s. After Smith's death in 1844, the movement split into several ...
and
Oregon Trail The Oregon Trail was a east–west, large-wheeled wagon route and Westward Expansion Trails, emigrant trail in the United States that connected the Missouri River to valleys in Oregon. The eastern part of the Oregon Trail spanned part of what ...
s as 6,000 to 12,000 are believed to have died on their way to
Utah Utah ( , ) is a state in the Mountain West subregion of the Western United States. Utah is a landlocked U.S. state bordered to its east by Colorado, to its northeast by Wyoming, to its north by Idaho, to its south by Arizona, and to it ...
and
Oregon Oregon () is a U.S. state, state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington (state), Washington, while the Snake River delineates much of it ...
in the cholera years of 1849–1855. It is believed cholera claimed more than 150,000 victims in the United States during the two pandemics between 1832 and 1849, and also claimed 200,000 victims in
Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...
. In Vietnam, cholera outbreak in 1849 killed estimatedly from 800,000 to one million people (8–10% of the kingdom's 1847 population).


1850s

The cholera epidemic in Russia that started in 1847 would last until 1851, killing over one million people. In 1851, a ship coming from Cuba carried the disease to
Gran Canaria Gran Canaria (, ; ), also Grand Canary Island, is the third-largest and second-most-populous island of the Canary Islands, an archipelago off the Atlantic coast of Northwest Africa which is part of Spain. the island had a population of that co ...
. It is considered that more than 6,000 people died in the island during summer, out of a population of 58,000. In 1852, cholera spread east to Indonesia, and later was carried to
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
and Japan in 1854. The
Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...
were infected in 1858 and
Korea Korea ( ko, 한국, or , ) is a peninsular region in East Asia. Since 1945, it has been divided at or near the 38th parallel, with North Korea (Democratic People's Republic of Korea) comprising its northern half and South Korea (Republic o ...
in 1859. In 1859, an outbreak in Bengal contributed to transmission of the disease by travelers and troops to
Iran Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkmeni ...
,
Iraq Iraq,; ku, عێراق, translit=Êraq officially the Republic of Iraq, '; ku, کۆماری عێراق, translit=Komarî Êraq is a country in Western Asia. It is bordered by Turkey to Iraq–Turkey border, the north, Iran to Iran–Iraq ...
,
Arabia The Arabian Peninsula, (; ar, شِبْهُ الْجَزِيرَةِ الْعَرَبِيَّة, , "Arabian Peninsula" or , , "Island of the Arabs") or Arabia, is a peninsula of Western Asia, situated northeast of Africa on the Arabian Plate. ...
and Russia. Japan suffered at least seven major outbreaks of cholera between 1858 and 1902. Between 100,000 and 200,000 people died of cholera in
Tokyo Tokyo (; ja, 東京, , ), officially the Tokyo Metropolis ( ja, 東京都, label=none, ), is the capital and largest city of Japan. Formerly known as Edo, its metropolitan area () is the most populous in the world, with an estimated 37.468 ...
in an outbreak in 1858–60. In 1854, an outbreak of cholera in
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
took the lives of 5.5 percent of the population (about 3,500 people).
Providence, Rhode Island Providence is the capital and most populous city of the U.S. state of Rhode Island. One of the oldest cities in New England, it was founded in 1636 by Roger Williams, a Reformed Baptist theologian and religious exile from the Massachusetts Bay ...
suffered an outbreak so widespread that for the next thirty years, 1854 was known there as "The Year of Cholera." In 1853–54, London's epidemic claimed 10,739 lives. In
Spain , image_flag = Bandera de España.svg , image_coat = Escudo de España (mazonado).svg , national_motto = ''Plus ultra'' (Latin)(English: "Further Beyond") , national_anthem = (English: "Royal March") , i ...
, over 236,000 died of cholera in the epidemic of 1854–55. The disease reached South America in 1854 and 1855, with victims in Venezuela and Brazil. During the third pandemic, Tunisia, which had not been affected by the two previous pandemics, thought Europeans had brought the disease. They blamed their sanitation practices. Some United States scientists began to believe that cholera was somehow associated with African Americans, as the disease was prevalent in the South in areas of black populations. Current researchers note their populations were underserved in terms of sanitation infrastructure, and health care, and they lived near the waterways by which travelers and ships carried the disease.


1854 Broad Street cholera outbreak

The
1854 Broad Street cholera outbreak Events January–March * January 4 – The McDonald Islands are discovered by Captain William McDonald aboard the ''Samarang''. * January 6 – The fictional detective Sherlock Holmes is perhaps born. * January 9 – The ...
was a severe
outbreak In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire ...
of
cholera Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and ...
that occurred in 1854 near Broad Street (now
Broadwick Street Broadwick Street (formerly Broad Street) is a street in Soho, City of Westminster, London. It runs for 0.18 miles (0.29 km) approximately west–east between Marshall Street and Wardour Street, crossing Berwick Street. Broad Street was no ...
) in the
Soho Soho is an area of the City of Westminster, part of the West End of London. Originally a fashionable district for the aristocracy, it has been one of the main entertainment districts in the capital since the 19th century. The area was develop ...
district of
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
,
England England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe b ...
, and occurred during the third cholera pandemic. This outbreak, which killed 616 people, is best known for the physician
John Snow John Snow (15 March 1813 – 16 June 1858) was an English physician and a leader in the development of anaesthesia and medical hygiene. He is considered one of the founders of modern epidemiology, in part because of his work in tracing the so ...
's study of its causes and his hypothesis that germ-contaminated water was the source of
cholera Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and ...
, rather than particles in the air (referred to as " miasma"). Snow identified the source of an 1854 cholera outbreak as the public water pump on Broad Street (now
Broadwick Street Broadwick Street (formerly Broad Street) is a street in Soho, City of Westminster, London. It runs for 0.18 miles (0.29 km) approximately west–east between Marshall Street and Wardour Street, crossing Berwick Street. Broad Street was no ...
). Although his studies were not entirely conclusive, his advocacy convinced the local council to disable the Broad Street pump by removing its handle. Snow later used a dot map to illustrate the cluster of cholera cases around the pump. He also used statistics to illustrate the connection between the quality of the water source and cholera cases, showing that water was being delivered to the outbreak area from sewage-polluted sections of the
Thames The River Thames ( ), known alternatively in parts as the River Isis, is a river that flows through southern England including London. At , it is the longest river entirely in England and the second-longest in the United Kingdom, after the R ...
, leading to an increased incidence of cholera. Snow's study was a major event in the history of public health and geography. It is regarded as one of the founding events of the science of
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
. This discovery came to influence
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
and the construction of improved
sanitation Sanitation refers to public health conditions related to clean drinking water and treatment and disposal of human excreta and sewage. Preventing human contact with feces is part of sanitation, as is hand washing with soap. Sanitation systems ...
facilities beginning in the mid-19th century. Later, the term "
focus of infection A focus of infection is a place containing whatever epidemiological factors are needed for transmission of an infection. Any focus of infection will have a source of infection, and other common traits of such a place include a human community, a v ...
" would be used to describe sites, such as the Broad Street pump, in which conditions are good for transmission of an infection. John Snow's endeavor to find the cause of the transmission of cholera caused him to unknowingly create a
double-blind experiment In a blind or blinded experiment, information which may influence the participants of the experiment is withheld until after the experiment is complete. Good blinding can reduce or eliminate experimental biases that arise from a participants' expec ...
.


See also

* History of cholera


References


External links


Book on Pandemics"> Book on Pandemics
{{DEFAULTSORT:Cholera Pandemic, 3 Cholera pandemics 19th-century health disasters 19th-century epidemics 1840s disease outbreaks 1850s disease outbreaks 1860s disease outbreaks