The 1951 Pont-Saint-Esprit mass poisoning, also known in French as Le Pain Maudit, was a mass poisoning on 15 August 1951, in the small town of
Pont-Saint-Esprit
Pont-Saint-Esprit (, literally "Holy Spirit Bridge"; oc, Lo Pònt Sant Esperit) is a commune in the Gard département in southern France. It is situated on the river Rhône and is the site of a historical crossing, hence its name. The Ardèche f ...
in
Southern France
Southern France, also known as the South of France or colloquially in French language, French as , is a defined geographical area consisting of the regions of France that border the Atlantic Ocean south of the Marais Poitevin,Louis Papy, ''Le midi ...
. More than 250 people were involved, including 50 people interned in
asylum
Asylum may refer to:
Types of asylum
* Asylum (antiquity), places of refuge in ancient Greece and Rome
* Benevolent Asylum, a 19th-century Australian institution for housing the destitute
* Cities of Refuge, places of refuge in ancient Judea
...
s and seven deaths. A
foodborne illness
Foodborne illness (also foodborne disease and food poisoning) is any illness resulting from the spoilage of contaminated food by pathogenic bacteria, viruses, or parasites that contaminate food,
as well as prions (the agents of mad cow disease) ...
was suspected; among these it was originally believed to be a case of "cursed bread" (''pain maudit'').
A majority of academic sources accept naturally occurring ergot poisoning as the cause of the epidemic, while a few theorize other causes such as poisoning by
mercury
Mercury commonly refers to:
* Mercury (planet), the nearest planet to the Sun
* Mercury (element), a metallic chemical element with the symbol Hg
* Mercury (mythology), a Roman god
Mercury or The Mercury may also refer to:
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* Merc ...
,
mycotoxins
A mycotoxin (from the Greek μύκης , "fungus" and τοξίνη , "toxin") is a toxic secondary metabolite produced by organisms of kingdom Fungi and is capable of causing disease and death in both humans and other animals. The term 'mycotoxin' ...
During the Vichy government, the supply of grains from field to mill to bakery was
directed
Director may refer to:
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* ''Director'' (magazine), a British magazine
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* Director (band), an Irish rock band
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by the government's grain control board, the Office National Interprofessionnel des Céréales (ONIC), and later the Union Meuniere. Essentially, this created a government monopoly on the sale of flour, allowing the government a measure of control over wartime supply shortages. This also meant that flour would be purchased directly from ONIC, and delivered to the baker for a set price, without the baker being able to have any control on quality. Following the end of the second world war, this system was relaxed, allowing for bakers to have some choice over their flour supply. ONIC retained its monopoly on inter-departmental exportation and importation. By this system, millers in departments with more supply than demand could sell the excess to ONIC. In practice, this meant that the higher-quality flour would be delivered to local bakers and lower-quality flour would be exported to other departments. Thus, departments with net flour deficits, like the
Gard
Gard () is a department in Southern France, located in the region of Occitanie. It had a population of 748,437 as of 2019;Issirac, at least 20 people reported cutaneous eruptions, diarrhea, vomiting and headaches. Similar symptoms were reported in
Laval-Saint-Roman
Laval-Saint-Roman (; oc, La Vau de Sant Roman) is a commune in the Gard department in southern France.
Population
See also
*Communes of the Gard department
This is a list of the 351 communes of the Gard department of France.
The commune ...
. Multiple families were reported sick in
Goudargues
Goudargues (; oc, Godargues) is a commune in the Gard department in southern France. Known locally as the ''Venise Gardoise'', because of the canal that flows through it centre. This is lined with pavement cafés and shaded by a two rows of ma ...
and Lamotte-du-Rhone.
In Connaux, the town's baker received reports from his clients that they believed his bread was causing violent diarrhea. He reported that his family, as well as himself, were all suffering from the same afflictions. The baker was quick to blame his flour, which he described as “bad, forming a sticky dough with acid fermentation” and which made gray and sticky bread.
In Saint-Genies-de-Comolas, the town's mayor was alerted by one of the town's two bakers that he received flour that was gray and full of worms. The mayor banned making bread with that flour, and referred the situation to the region's prefect, as well as to the driver that delivered the flour.
The delivery driver, Jean Bousquet, sent the prefect a copy of a remark made to his employer, the miller's union in Nimes, on 9 August. The note said that “almost every baker of Centre de Bagnols/Cèze has complained of the quality of the flour provided by Mr. Maillet”. Following the incident at Connaux, Bousquet requested immediate written instructions from his employer regarding the situation. On the 13th of August, he requested that samples be taken to determine if the flour was contaminated. During this period, 42 bakers complained of the flour delivered by Bousquet.
Mass poisoning
On 16 August 1951, the local offices of the town's two doctors filled with patients reporting similar food poisoning symptoms; nausea, vomiting, cold chills, heat waves. These symptoms eventually worsened, with added hallucinatory crises and convulsions. The situation in the town deteriorated in the following days. On the night of 24 August, a man believed himself to be an aeroplane and died by jumping from a second-story window, and an 11-year-old boy tried to strangle his mother. One of the town's two doctors would name the night ''nuit d'apocalypse;'' apocalyptic night.
Epidemiological investigation
Doctors Vieu and Gabbai investigated the epidemiology of the disease. On 19 August, they came to the conclusion that bread was to blame; all patients interrogated had purchased their bread at the Briand bakery in Pont-Saint-Esprit. In a family from a neighboring village four of whose nine members fell ill, all members who ate bread from the Briand bakery fell ill, whereas none of the others who ate bread from another bakery did. Another family shared a loaf of Briand's bread among five of its seven members, the others preferring biscottes, with only the five falling ill.
On the morning of the 20th, the health service, the prefecture, the prosecutor of the Republic and the police were notified. Roch Briand was interrogated, and the sickness in the town was blamed on his bread.
Criminal investigation
The police investigation would eventually center on the second of three batches of bread made at Briand's bakery on the day of 16 August. The flour composition of each batch varied, as having run out of flour during the preparation of the second batch, Briand had borrowed flour from two other local bakers, Jaussent and Fallavet. Briand's assistant stated that when he picked up flour from Jaussent, the baker was out ill, and that he took the flour from his assistant instead.
Both Briand and his assistant agreed that the first batch was constituted of the previous day's flour mixed with flour borrowed from Jaussent. They disagreed on the second and third batches. Whereas Briand stated that the second was made with Jaussent's flour and the third with Fallavet's flour, the assistant stated that both latter batches were made with a mix of the two.
The investigation led police to interrogate many of the town's residents, who gave inconsistent ratings of Briand's tainted batch. Some reported that the taste was perfectly normal, while others reported chemical smells (one described an odor of gasoline, another of bleach). Some reported that the bread looked normal, while others stated that its appearance was grayish.
Inquiry
On the 23rd of August, a judge of inquiry opened a formal investigation, and tasked commissaire Georges Sigaud with finding the cause of the mass poisoning event.
The tainted bread made by Briand was made with only four ingredients: flour, yeast, water and salt. All of the ingredients but the flour could be easily discounted as sources of the illness. The water used to make the bread was from a municipal source, the same that also supplied the rest of the village. Both the salt and the yeast used by Briand were sourced from the same suppliers as all other bakers in the region, and subsequent testing of the supplies found no toxicity.
The investigation of the provenance of the flour led Sigaud to the UM-Gard flour distribution centre, in Bagnols-sur-Cèze. The chief of the distribution network, Jean Bousquet, stated that since the end of July, the vast majority of the flour supplying the region was from two mills; one in
Châtillon-sur-Indre
Châtillon-sur-Indre (, literally ''Châtillon on Indre'') is a commune in the Indre department, central France.
Population
See also
*Communes of the Indre department
The following is a list of the 241 communes of the Indre department of F ...
, and the other being the mill of Maurice Maillet in Saint-Martin-la-Rivière, the latter of which was the subject of numerous complaints about the quality of its flour.
Maurice Maillet
In an interrogation that lasted multiple hours, Maurice Maillet denied mixing rye (which is highly susceptible to ergot) into his flour, opting instead to cut his product with 2% of
bean
A bean is the seed of several plants in the family Fabaceae, which are used as vegetables for human or animal food. They can be cooked in many different ways, including boiling, frying, and baking, and are used in many traditional dishes th ...
flour. This was unusual, given that owing to a shortage of wheat, ONIC had mandated that rye flour be mixed in. However, in the Vienne department, rye of good quality was often more expensive than wheat, and accordingly, bean flour was authorised by ONIC as a replacement.
Despite this, it came to light that the supply of grains to be milled for export was sometimes mixed with grains milled in an informal agreement called ''échangisme''. Under this type of agreement, often practiced at the time, a farmer would bring a baker grain he grew himself in exchange for bread that would later be made with his grain. The baker would bring the grain to the miller, who would mill it. The miller and baker would each take a cut for sale.
During the interrogation, Maillet admitted that he had made a deal with a baker, Guy Bruère, who had brought in bags to be milled. Since this was near the end of the season, the bags were filled with leftover grain that sometimes contained a high proportion of rye. The rye was not the only problem with the flour, as the miller also noted the presence of
weevils
Weevils are beetles belonging to the superfamily Curculionoidea, known for their elongated snouts. They are usually small, less than in length, and herbivorous. Approximately 97,000 species of weevils are known. They belong to several families, ...
, mites and dust. The baker was concerned that he would lose business should he refuse the grain on the basis of quality. Despite the miller having noticed the low quality of the grains, he agreed to exchange the grain for a lower quantity of flour already milled from grain marked for export. Given that the quantity of lower-quality grain was much lower than that of the grain for export, the miller thought that it would be possible to mix it all without reducing the overall quality of the flour.
Arrests and trial
On August 31, around 14:30, Sigaud addressed the media, announcing the arrests of Maillet and Bruère for
involuntary manslaughter
Manslaughter is a common law legal term for homicide considered by law as less culpable than murder. The distinction between murder and manslaughter is sometimes said to have first been made by the ancient Athenian lawmaker Draco in the 7th c ...
and involuntary injuries arising from their negligence in trading improper flour. Further arrests were made in the following days: an employee of Maillet, André Bertrand, was arrested, but released on bail as he was the head of a family of nine whose wife was about to give birth. The owners of the bakery at which Bruère was employed, Clothaire and Denise Audidier, were also arrested for infractions of fiscal legislation and of legislation governing wheat and flour.
Scientific publishing
Shortly after the incident, in September 1951, Dr. Gabbai and colleagues published a paper in the ''British Medical Journal'' declaring that "the outbreak of poisoning" was produced by ergot fungus. The victims appeared to have one common connection. They had eaten bread from the bakery of Roch Briand, who was subsequently blamed for having used flour made from contaminated rye. Animals who had eaten the bread were also found to have perished. According to reports at the time, the flour had been contaminated by the fungus ''Claviceps purpurea'' (ergot), which produces alkaloids that are structurally similar to the hallucinogenic drug
lysergic acid diethylamide
Lysergic acid diethylamide (LSD), also known colloquially as acid, is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception. At sufficiently high dosages LSD manifests primarily mental, vi ...
(
LSD
Lysergic acid diethylamide (LSD), also known colloquially as acid, is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception. At sufficiently high dosages LSD manifests primarily mental, vi ...
fungicide
Fungicides are biocidal chemical compounds or biological organisms used to kill parasitic fungi or their spores. A fungistatic inhibits their growth. Fungi can cause serious damage in agriculture, resulting in critical losses of yield, quality, ...
s to treat grain and seeds.
This type of contamination was considered owing to the presence of fluorescent stains on the outside of some used empty flour bags returned to the distributor. Panogen was sold containing a red colorant as a safety measure, to ensure that seeds coated with it would be used only for planting. Subsequent scientific tests showed that this coloring would not penetrate flour bags but that the active ingredient could do so. This would allow contamination of the flour, but it would appear to be limited to the bags. Further testing showed that if bread were to be baked using Panogen-contaminated flour, the rising of the bread could be partially or totally inhibited, depending on the concentration. This hypothesis was considered thoroughly in a French civil trial arising from the accident, with the contamination mechanism being a train wagon carrying flour that could have previously carried concentrated cylinders of Panogen intended for agricultural uses. It was later discovered that pre-treating the seeds in Panogen could lead to mercury accumulation in the plants growing from those seeds. For this reason, Panogen, made by a Swedish company, was banned in Sweden in 1966. A revised version of the ban, in 1970, would prohibit the exportation of Panogen, leading to its removal from the market.
In 1982, a French researcher suggested ''
Aspergillus fumigatus
''Aspergillus fumigatus'' is a species of fungus in the genus ''Aspergillus'', and is one of the most common ''Aspergillus'' species to cause disease in individuals with an immunodeficiency.
''Aspergillus fumigatus'', a saprotroph widespread in ...
grain silo
A grain is a small, hard, dry fruit (caryopsis) – with or without an attached hull layer – harvested for human or animal consumption. A grain crop is a grain-producing plant. The two main types of commercial grain crops are cereals and legumes ...
s, as a potential culprit.
Historian Steven Kaplan's 2008 book, ''Le Pain Maudit'' states that the poisoning might have been caused by nitrogen trichloride used to artificially (and illegally) bleach flour.Quand le pain empoisonne ''La Vie des idées'', 3 September 2008 (in French)
In his 2009 book, ''A Terrible Mistake,'' author and investigative journalist Hank P. Albarelli Jr claims that the Special Operations Division of the
Central Intelligence Agency
The Central Intelligence Agency (CIA ), known informally as the Agency and historically as the Company, is a civilian foreign intelligence service of the federal government of the United States, officially tasked with gathering, processing, ...
(CIA) tested the use of LSD on the population of Pont-Saint-Esprit as part of its
MKNAOMI
MKNAOMI is the code name for a joint Department of Defense/CIA research program from the 1950s through to the 1970s. Unclassified information about the MKNAOMI program and the related Special Operations Division is scarce. It is generally reported ...
biological warfare program, in a field test called "Project SPAN". According to Albarelli, this is based on CIA documents held in the US National Archives and a document supplied to the 1975
Rockefeller Commission #REDIRECT United States President's Commission on CIA Activities within the United States
{{R from move ...
that investigated CIA activities. Albarelli's view was reported widely after the book's publication, including by ''
The Daily Telegraph
''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a national British daily broadsheet newspaper published in London by Telegraph Media Group and distributed across the United Kingdom and internationally.
It was fo ...
'', France 24 and BBC News. The attribution of the poisoning to the CIA in Albarelli's book has been roundly criticized. Historian Steven Kaplan, author of an earlier book about the events, said that this would be "clinically incoherent: LSD takes effects in just a few hours, whereas the inhabitants showed symptoms only after 36 hours or more. Furthermore, LSD does not cause the digestive ailments or the vegetative effects described by the townspeople."
In popular culture
Barbara Comyns
Barbara Irene Veronica Comyns Carr (born Barbara Irene Veronica Bayley; 27 December 1907Celia Brayfield (2004)Carr, Barbara Irene Veronica Comyns (1907–1992) ''Oxford Dictionary of National Biography''. Oxford: Oxford University Press. – 14 ...
wrote her third novel, ''Who Was Changed and Who Was Dead'' (1954), after reading about the poisoning.
Sophie Mackintosh's third novel, ''Cursed Bread'' (2023) is based on the poisoning.