16-Methylene-17α-hydroxyprogesterone acetate is a progestin of the

17α-hydroxyprogesterone 17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many o ...

group which was never marketed. Given orally, it shows about 2.5-fold the progestogenic activity of

parenteral A route of administration in pharmacology and toxicology is the way by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. ...

progesterone in animal

bioassay A bioassay is an analytical method to determine the concentration or potency of a substance by its effect on living animals or plants (''in vivo''), or on living cells or tissues(''in vitro''). A bioassay can be either quantal or quantitative, dir ...

s. It is a

parent compound In chemistry, a parent structure is the structure of an unadorned ion or molecule from which derivatives can be visualized. Parent structures underpin systematic nomenclature and facilitate classification. Fundamental parent structures have on ...

of the following clinically used progestins: * Chlormethenmadinone acetate (6-chloro-16-methylene-17α-hydroxy-Δ⁶-progesterone acetate) * Melengestrol acetate (6-methyl-16-methylene-17α-hydroxy-Δ⁶-progesterone acetate) * Methenmadinone acetate (16-methylene-17α-hydroxy-Δ⁶-progesterone acetate) *

Segesterone acetate Segesterone acetate (SGA), sold under the brand names Nestorone, Elcometrine, and Annovera, is a progestin medication which is used in birth control and in the treatment of endometriosis in the United States, Brazil, and other South American coun ...

(16-methylene-17α-hydroxy-19-norprogesterone acetate)

References

Abandoned drugs Acetate esters Diketones Pregnanes Progestogens Vinylidene compounds {{Genito-urinary-drug-stub