11-Hydroxy-Delta-8-tetrahydrocannabinol (11-OH-Δ
8-THC, alternatively numbered as 7-OH-Δ
6-THC) is an
active metabolite An active metabolite is an active form of a drug after it has been processed by the body.
Metabolites of drugs
An active metabolite results when a drug is metabolized by the body into a modified form which continues to produce effects in the body ...
of
Delta-8-THC (Δ
8-THC), a psychoactive cannabinoid found in small amounts in
cannabis. It is an isomer of
11-OH-Δ9-THC, and is produced via the same metabolic pathway. It was the first cannabinoid metabolite discovered in 1970.
It retains psychoactive effects in animal studies with higher potency than Δ
8-THC but lower potency than
11-OH-Δ9-THC. With widespread legal use of semi-synthetic Δ
8-THC in jurisdictions where Δ
9-THC remains illegal, 11-OH-Δ
8-THC is now an important metabolite for distinguishing between use of legal Δ
8-THC and illegal Δ
9-THC.
See also
*
3'-Hydroxy-THC
3'-Hydroxy-THC (3'-OH-Δ9-THC) is a minor active metabolite of THC, the main psychoactive component of cannabis. It is one of a number of metabolites of THC hydroxylated on the pentyl side chain, but while the other side-chain hydroxyl isomers ar ...
*
7-Hydroxycannabidiol
*
8,11-Dihydroxytetrahydrocannabinol
*
9-OH-HHC
*
11-OH-HHC
11-Hydroxyhexahydrocannabinol (11-OH-9α-HHC and 11-OH-9β-HHC, or alternatively 7-OH-HHC under the benzopyran numbering system) is an active metabolite of tetrahydrocannabinol (THC) and the major metabolite of the trace cannabinoid hexahydrocann ...
*
11-OH-CBN
11-Hydroxycannabinol (11-OH-CBN) is the main active metabolite of cannabinol (CBN), one of the active components of cannabis, and has also been isolated from cannabis itself. It is more potent than CBN itself, acting as an agonist of CB1 with aro ...
*
11-Nor-9-carboxy-THC
11-Nor-9-carboxy-Δ9-tetrahydrocannabinol (11-COOH-THC or THC-COOH), often referred to as 11-nor-9-carboxy-THC or THC-11-oic acid, is the main secondary metabolite of tetrahydrocannabinol (THC) which is formed in the body after cannabis is consu ...
*
Delta-6-Cannabidiol
Delta-6-cannabidiol (∆6-CBD) is a positional isomer of cannabidiol, found in only trace amounts in natural cannabis plants but readily synthesised from cannabidiol by base-catalysed migration of the double bond.
See also
* 4'-Fluorocannabidio ...
*
Delta-10-THC
*
HU-210
References
Cannabinoids
Benzochromenes
{{cannabinoid-stub