1-Hydroxy-7-azabenzotriazole (HOAt) is a

triazole A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C2H3N3. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within t ...

used as a

peptide coupling reagent In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl ...

. It suppresses the

racemization In chemistry, racemization is a conversion, by heat or by chemical reaction, of an optically active compound into a racemic (optically inactive) form. This creates a 1:1 molar ratio of enantiomers and is referred too as a racemic mixture (i.e. con ...

. HOAt has a melting point between 213 and 216 degrees Celsius. As a liquid, it is transparent and without any color.

References

Peptide coupling reagents Triazolopyridines Reagents for biochemistry Hydroxylamines {{heterocyclic-stub