1-Fluornaphthalene is an
organofluorine
Organofluorine chemistry describes the chemistry of the organofluorines, organic compounds that contain the carbon–fluorine bond. Organofluorine compounds find diverse applications ranging from oil and water repellents to pharmaceuticals, ref ...
chemical compound from the group of naphthalene derivatives and fluoroaromatics. Its chemical formula is .
Synthesis
1-Fluoronaphthalene can be obtained by reacting
naphthalene with
Selectfluor
Selectfluor, a trademark of Air Products and Chemicals, is a reagent in chemistry that is used as a fluorine donor. This compound is a derivative of the nucleophillic base DABCO. It is a colourless salt that tolerates air and even water. It has ...
.
Properties
1-Fluoronaphthalene is a colorless, combustible liquid, which is insoluble in water.
Applications
1-Fluoronaphthalene was used for the
''tert''-butyllithium-mediated synthesis of 6-substituted
phenanthridine
Phenanthridine is a nitrogen heterocyclic compound that is the basis of DNA-binding fluorescent dyes through intercalation. Examples of such dyes are ethidium bromide and propidium iodide. Acridine is an isomer of phenanthridine.
Phenanthridine ...
s. It has also been used in the synthesis of LY248686, a potent inhibitor of
serotonin and
norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name "noradrenaline" (from Latin '' ad' ...
uptake.
1-Fluoronaphthalene is also used as a component of the Organic Check Material mounted in canisters on
Mars Science Laboratory
Mars Science Laboratory (MSL) is a robotic space probe mission to Mars launched by NASA on November 26, 2011, which successfully landed ''Curiosity'', a Mars rover, in Gale Crater on August 6, 2012. The overall objectives include investigati ...
''Curiosity'' rover. It's used for calibrating the
Sample Analysis at Mars
Sample Analysis at Mars (SAM) is a suite of instruments on the Mars Science Laboratory ''Curiosity'' rover. The SAM instrument suite will analyze organics and gases from both atmospheric and solid samples.
It was developed by the NASA Goddard S ...
(SAM) instrument suite, being a synthetic organic compound not found in nature on Earth and not expected on Mars.
See also
*
1-Bromonaphthalene
1-Bromonaphthalene is an organic compound with the formula C10H7Br. It is one of two isomeric bromonaphthalenes, the other being 2-bromonaphthalene. Under normal conditions, the substance is a colorless liquid.
Synthesis and reactions
It is pre ...
*
1-Chloronaphthalene
References
{{DEFAULTSORT:Fluoronaphthalene, 1-
Fluoroarenes
1-Naphthyl compounds