Zofenoprilat
Zofenoprilat is an angiotensin-converting enzyme inhibitor, and is the free sulfhydryl In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl grou ... active metabolite of zofenopril. References Agents acting on the renin-angiotensin system Thiols Human drug metabolites Carboxylic acids {{drug-stub ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  

Zofenopril
Zofenopril ( INN) is a medication that protects the heart and helps reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor. In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs, atenolol and enalapril, and was associated with fewer adverse effects. Zofenopril is a prodrug A prodrug is a medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug ... with zofenoprilat as the active metabolite. It was patented in 1978 and approved for medical use in 2000. References ACE inhibitors Carboxamides Enantiopure drugs Prodrugs Pyrrolidines {{cardiovascular-drug-stub ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]