|
Windkessel Effect
Windkessel effect is a term used in medicine to account for the shape of the arterial blood pressure waveform in terms of the interaction between the stroke volume and the compliance of the aorta and large elastic arteries (Windkessel vessels) and the resistance of the smaller arteries and arterioles. Windkessel when loosely translated from German to English means 'air chamber', but is generally taken to imply an ''elastic reservoir''. The walls of large elastic arteries (e.g. aorta, common carotid, subclavian, and pulmonary arteries and their larger branches) contain elastic fibers, formed of elastin. These arteries distend when the blood pressure rises during systole and recoil when the blood pressure falls during diastole. Since the rate of blood entering these elastic arteries exceeds that leaving them via the peripheral resistance, there is a net storage of blood in the aorta and large arteries during systole, which discharges during diastole. The compliance (or distensi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Windkessel Effect
Windkessel effect is a term used in medicine to account for the shape of the arterial blood pressure waveform in terms of the interaction between the stroke volume and the compliance of the aorta and large elastic arteries (Windkessel vessels) and the resistance of the smaller arteries and arterioles. Windkessel when loosely translated from German to English means 'air chamber', but is generally taken to imply an ''elastic reservoir''. The walls of large elastic arteries (e.g. aorta, common carotid, subclavian, and pulmonary arteries and their larger branches) contain elastic fibers, formed of elastin. These arteries distend when the blood pressure rises during systole and recoil when the blood pressure falls during diastole. Since the rate of blood entering these elastic arteries exceeds that leaving them via the peripheral resistance, there is a net storage of blood in the aorta and large arteries during systole, which discharges during diastole. The compliance (or distensi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peripheral Resistance
Vascular resistance is the resistance that must be overcome to push blood through the circulatory system and create flow. The resistance offered by the systemic circulation is known as the systemic vascular resistance (SVR) or may sometimes be called by the older term total peripheral resistance (TPR), while the resistance offered by the pulmonary circulation is known as the pulmonary vascular resistance (PVR). Systemic vascular resistance is used in calculations of blood pressure, blood flow, and cardiac function. Vasoconstriction (i.e., decrease in blood vessel diameter) increases SVR, whereas vasodilation (increase in diameter) decreases SVR. Units for measuring Units for measuring vascular resistance are dyn·s·cm−5, pascal seconds per cubic metre (Pa·s/m3) or, for ease of deriving it by pressure (measured in mmHg) and cardiac output (measured in L/min), it can be given in mmHg·min/L. This is numerically equivalent to hybrid resistance units (HRU), also known as Wood uni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Circulatory System
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek ''kardia'' meaning ''heart'', and from Latin ''vascula'' meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with the ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The Closed circulatory system, circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Some in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electric Potential
The electric potential (also called the ''electric field potential'', potential drop, the electrostatic potential) is defined as the amount of work energy needed to move a unit of electric charge from a reference point to the specific point in an electric field. More precisely, it is the energy per unit charge for a test charge that is so small that the disturbance of the field under consideration is negligible. Furthermore, the motion across the field is supposed to proceed with negligible acceleration, so as to avoid the test charge acquiring kinetic energy or producing radiation. By definition, the electric potential at the reference point is zero units. Typically, the reference point is earth or a point at infinity, although any point can be used. In classical electrostatics, the electrostatic field is a vector quantity expressed as the gradient of the electrostatic potential, which is a scalar quantity denoted by or occasionally , equal to the electric potential energy o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Differential Equation
In mathematics, a differential equation is an equation that relates one or more unknown functions and their derivatives. In applications, the functions generally represent physical quantities, the derivatives represent their rates of change, and the differential equation defines a relationship between the two. Such relations are common; therefore, differential equations play a prominent role in many disciplines including engineering, physics, economics, and biology. Mainly the study of differential equations consists of the study of their solutions (the set of functions that satisfy each equation), and of the properties of their solutions. Only the simplest differential equations are solvable by explicit formulas; however, many properties of solutions of a given differential equation may be determined without computing them exactly. Often when a closed-form expression for the solutions is not available, solutions may be approximated numerically using computers. The theory of d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Otto Frank (physiologist)
Otto Frank (21 June 1865 – 12 November 1944) was a German born doctor and physiologist who made contributions to cardiac physiology and cardiology. The Frank–Starling law of the heart is named after him and Ernest Starling. Family and early life (Friedrich Wilhelm Ferdinand) Otto Frank was born in Groß-Umstadt and was the son of Georg Frank (1838–1907), a doctor of medicine and a practicing physician, and Mathilde Lindenborn (1841–1906). Otto Frank was married to Theres Schuster in a Catholic wedding in Munich. Training and Work Otto Frank studied medicine in Munich and Kiel between 1884 and 1889 (approbation in Munich 1889). During 1889 to 1891 he undertook training in mathematics, chemistry, physics, anatomy and zoology in Heidelberg, Glasgow, Munich and Straßburg. He then worked until 1894 as an assistant to Carl Friedrich Wilhelm Ludwig in the ''Physiologisches Institut'' in Leipzig. There in 1892 he completed his doctoral studies (''Promotion''). Subsequently, fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stephen Hales
Stephen Hales (17 September 16774 January 1761) was an English clergyman who made major contributions to a range of scientific fields including botany, pneumatic chemistry and physiology. He was the first person to measure blood pressure. He also invented several devices, including a ventilator, a pneumatic trough and a surgical forceps for the removal of bladder stones. In addition to these achievements, he was a philanthropist and wrote a popular tract on alcoholic intemperance. Life Stephen Hales was born in Bekesbourne, Kent, England. He was the sixth son of Thomas Hales, heir to Baronetcy of Beakesbourne and Brymore, and his wife, Mary (née Wood), and was one of twelve or possibly thirteen children.Archibald Edmund Clark-Kennedy. Stephen Hales, D.D., F.R.S.: an eighteenth century biography. Cambridge University Press, 1929. Thomas Hales (died 1692) predeceased his father, Sir Robert Hales; therefore Sir Robert's grandson, Sir Thomas Hales, 2nd Baronet (Stephen Hales' br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Giovanni Borelli
Giovanni Alfonso Borelli (; 28 January 1608 – 31 December 1679) was a Renaissance Italian physiologist, physicist, and mathematician. He contributed to the modern principle of scientific investigation by continuing Galileo's practice of testing hypotheses against observation. Trained in mathematics, Borelli also made extensive studies of Jupiter's moons, the mechanics of animal locomotion and, in microscopy, of the constituents of blood. He also used microscopy to investigate the stomatal movement of plants, and undertook studies in medicine and geology. During his career, he enjoyed the patronage of Queen Christina of Sweden. Biography Giovanni Borelli was born on 28 January 1608 in the district of Castel Nuovo, in Naples. He was the son of Spanish infantryman Miguel Alonso and a local woman named Laura Porello (alternately ''Porelli'' or ''Borelli''.) Borelli eventually traveled to Rome where he studied under Benedetto Castelli, matriculating in mathematics at Sapien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Cycle
The cardiac cycle is the performance of the human heart from the beginning of one heartbeat to the beginning of the next. It consists of two periods: one during which the heart muscle relaxes and refills with blood, called diastole, following a period of robust contraction and pumping of blood, called systole. After emptying, the heart immediately relaxes and expands to receive another influx of blood returning from the lungs and other systems of the body, before again contracting to pump blood to the lungs and those systems. A normally performing heart must be fully expanded before it can efficiently pump again. Assuming a healthy heart and a typical rate of 70 to 75 beats per minute, each cardiac cycle, or heartbeat, takes about 0.8 second to complete the cycle. There are two atrial and two ventricle chambers of the heart; they are paired as the left heart and the right heart—that is, the left atrium with the left ventricle, the right atrium with the right ventricle—and t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulse Pressure
Pulse pressure is the difference between systolic and diastolic blood pressure. It is measured in millimeters of mercury (mmHg). It represents the force that the heart generates each time it contracts. Resting blood pressure is normally approximately 120/80 mmHg, which yields a pulse pressure of approximately 40 mm Hg. Causes High High sodium intake may cause high pulse pressure. Calculation Pulse pressure is the (higher) systolic blood pressure minus the (lower) diastolic blood pressure. The systemic pulse pressure is approximately proportional to stroke volume, or the amount of blood ejected from the left ventricle during systole (pump action) and inversely proportional to the compliance (similar to Elasticity) of the aorta. The aorta has the highest compliance in the arterial system due in part to a relatively greater proportion of elastin fibers versus smooth muscle and collagen. This serves the important function of damping the pulsatile ( max pump pressure) ou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Damping Ratio
Damping is an influence within or upon an oscillatory system that has the effect of reducing or preventing its oscillation. In physical systems, damping is produced by processes that dissipate the energy stored in the oscillation. Examples include viscous drag (a liquid's viscosity can hinder an oscillatory system, causing it to slow down; see viscous damping) in mechanical systems, resistance in electronic oscillators, and absorption and scattering of light in optical oscillators. Damping not based on energy loss can be important in other oscillating systems such as those that occur in biological systems and bikes (ex. Suspension (mechanics)). Not to be confused with friction, which is a dissipative force acting on a system. Friction can cause or be a factor of damping. The damping ratio is a dimensionless measure describing how oscillations in a system decay after a disturbance. Many systems exhibit oscillatory behavior when they are disturbed from their position of sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Stephen Hales")
