Ventricular-brain Ratio
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Ventricular-brain Ratio
Ventricular-brain ratio (VBR), also known as the ventricle-to-brain ratio or ventricle-brain ratio, is the ratio of total ventricle area to total brain area, which can be calculated with planimetry from brain imagining techniques such as CT scans. (). . It is a common measure of ventricular dilation or cerebral atrophy in patients with traumatic brain injury or hydrocephalus ''ex vacuo''. VBR also tends to increase with age. Generally, a higher VBR means a worse prognosis for recovering from a brain injury. For example, VBR is significantly correlated with performance on the Luria-Nebraska neuropsychological battery. Studies have found people with schizophrenia have larger third ventricles and VBR. Correlational studies have found relationships between ventricle-brain ratio and binge eating and inversely with plasma thyroid hormone concentration. See also * Sarnoff A. Mednick Sarnoff Andrei Mednick, (January 27, 1928 – April 10, 2015) was a psychologist who pioneer ...
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Ventricular System
The ventricular system is a set of four interconnected cavities known as cerebral ventricles in the brain. Within each ventricle is a region of choroid plexus which produces the circulating cerebrospinal fluid (CSF). The ventricular system is continuous with the central canal of the spinal cord from the fourth ventricle, allowing for the flow of CSF to circulate. All of the ventricular system and the central canal of the spinal cord are lined with ependyma, a specialised form of epithelium connected by tight junctions that make up the blood–cerebrospinal fluid barrier. Structure The system comprises four ventricles: * lateral ventricles right and left (one for each hemisphere) * third ventricle * fourth ventricle There are several foramina, openings acting as channels, that connect the ventricles. The interventricular foramina (also called the foramina of Monro) connect the lateral ventricles to the third ventricle through which the cerebrospinal fluid can flow. Ventric ...
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Planimetry
Planimetrics is the study of plane measurements, including angles, distances, and areas. History To measure planimetrics a planimeter or dot planimeter is used. This rather advanced analog technology is being taken over by simple image measurement software tools like, ImageJ, Adobe Acrobat, Google Earth Pro, Gimp GIMP ( ; GNU Image Manipulation Program) is a free and open-source raster graphics editor used for image manipulation (retouching) and image editing, free-form drawing, transcoding between different image file formats, and more specialized task ..., Photoshop and KLONK Image Measurement which can help do this kind of work from digitalized images. In geography Planimetric elements in geography are those features that are independent of elevation, such as roads, building footprints, and rivers and lakes. They are represented on two-dimensional maps as they are seen from the air, or in aerial photography. These features are often digitized from orthorectified a ...
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CT Scan
A computed tomography scan (CT scan; formerly called computed axial tomography scan or CAT scan) is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or radiology technologists. CT scanners use a rotating X-ray tube and a row of detectors placed in a gantry (medical), gantry to measure X-ray Attenuation#Radiography, attenuations by different tissues inside the body. The multiple X-ray measurements taken from different angles are then processed on a computer using tomographic reconstruction algorithms to produce Tomography, tomographic (cross-sectional) images (virtual "slices") of a body. CT scans can be used in patients with metallic implants or pacemakers, for whom magnetic resonance imaging (MRI) is Contraindication, contraindicated. Since its development in the 1970s, CT scanning has proven to be a versatile imaging technique. While CT is most prominently used in medical diagnosis, ...
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Traumatic Brain Injury
A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. TBI can be classified based on severity (ranging from mild traumatic brain injury TBI/concussionto severe traumatic brain injury), mechanism ( closed or penetrating head injury), or other features (e.g., occurring in a specific location or over a widespread area). Head injury is a broader category that may involve damage to other structures such as the scalp and skull. TBI can result in physical, cognitive, social, emotional and behavioral symptoms, and outcomes can range from complete recovery to permanent disability or death. Causes include falls, vehicle collisions and violence. Brain trauma occurs as a consequence of a sudden acceleration or deceleration within the cranium or by a complex combination of both movement and sudden impact. In addition to the damage caused at the moment of injury, a variety of events following the injury may result in ...
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Hydrocephalus
Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the brain. This typically causes increased intracranial pressure, pressure inside the skull. Older people may have headaches, double vision, poor balance, urinary incontinence, personality changes, or mental impairment. In babies, it may be seen as a rapid increase in head size. Other symptoms may include vomiting, sleepiness, seizures, and Parinaud's syndrome, downward pointing of the eyes. Hydrocephalus can occur due to birth defects or be acquired later in life. Associated birth defects include neural tube defects and those that result in aqueductal stenosis. Other causes include meningitis, brain tumors, traumatic brain injury, intraventricular hemorrhage, and subarachnoid hemorrhage. The four types of hydrocephalus are communicating, noncommunicating, ''ex vacuo'', and normal pressure hydrocephalus, normal pressure. Diagnosis is typically made by physical examination and medic ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months (DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2 ...
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Third Ventricle
The third ventricle is one of the four connected ventricles of the ventricular system within the mammalian brain. It is a slit-like cavity formed in the diencephalon between the two thalami, in the midline between the right and left lateral ventricles, and is filled with cerebrospinal fluid (CSF). Running through the third ventricle is the interthalamic adhesion, which contains thalamic neurons and fibers that may connect the two thalami. Structure The third ventricle is a narrow, laterally flattened, vaguely rectangular region, filled with cerebrospinal fluid, and lined by ependyma. It is connected at the superior anterior corner to the lateral ventricles, by the interventricular foramina, and becomes the cerebral aqueduct (''aqueduct of Sylvius'') at the posterior caudal corner. Since the interventricular foramina are on the lateral edge, the corner of the third ventricle itself forms a bulb, known as the ''anterior recess'' (it is also known as the ''bulb of the ventricl ...
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Binge Eating
Binge eating is a pattern of disordered eating which consists of episodes of uncontrollable eating. It is a common symptom of eating disorders such as binge eating disorder and bulimia nervosa. During such binges, a person rapidly consumes an excessive quantity of food. A Medical diagnosis, diagnosis of binge eating is associated with feelings of loss of control. Binge eating disorder is also linked with being overweight and obesity. Diagnosis The DSM-5 includes a disorder diagnosis criteria for Binge eating disorder, Binge Eating Disorder (BED). It is as follows: * Recurrent and persistent episodes of binge eating * Binge eating episodes are associated with three (or more) of the following: ** Eating much more rapidly than normal ** Eating until feeling uncomfortably full ** Eating large amounts of food when not physically hungry ** Eating alone because of being embarrassed by how much one is eating ** Feeling disgusted with oneself, depressed, or very guilty after overeati ...
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Thyroid Hormone
File:Thyroid_system.svg, upright=1.5, The thyroid system of the thyroid hormones T3 and T4 rect 376 268 820 433 Thyroid-stimulating hormone rect 411 200 849 266 Thyrotropin-releasing hormone rect 297 168 502 200 Hypothalamus rect 66 216 386 256 Anterior pituitary gland rect 66 332 342 374 Negative feedback rect 308 436 510 475 Thyroid gland rect 256 539 563 635 Thyroid hormones rect 357 827 569 856 Catecholamine rect 399 716 591 750 Metabolism desc bottom-left Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine (T3) and thyroxine (T4). They are tyrosine-based hormones that are primarily responsible for regulation of metabolism. T3 and T4 are partially composed of iodine. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyroid tissue and will cause the disease known as simple goitre. The major form of thyroid hormone in the blood is thyroxine (T4), whose half-life of around one week is longer th ...
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Sarnoff A
Sarnoff is a surname which may refer to: * Dan Sarnoff(born c.1956), *Ann Sarnoff (born c. 1962), American businesswoman *Arthur Sarnoff (1912–2000), American artist *David Sarnoff (1891–1971), Belarusian-born American radio and television technology pioneer and businessman *Dorothy Sarnoff (1914–2008), American operatic soprano, musical theatre actress and image consultant *Elizabeth Sarnoff, American television writer and producer *Robert W. Sarnoff, American businessman * Sarnoff A. Mednick (1928–2015) *Stanley Sarnoff Stanley J. Sarnoff (April 5, 1917 – May 23, 1990) was an American doctor who produced over 200 papers and 60 patents during his long career. His work included the development of such widely used devices as the "auto-injector," which included the ... (died 1990), surgeon and inventor of medical devices {{surname Jewish surnames ...
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