Vasopressin Arginine System
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Vasopressin Arginine System
Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized from the AVP gene as a peptide Hormone, prohormone in neurons in the hypothalamus, and is converted to AVP. It then travels down the axon terminating in the posterior pituitary, and is released from Synaptic vesicle, vesicles into the circulation in response to extracellular fluid Tonicity, hypertonicity (Renal physiology, hyperosmolality). AVP has two primary functions. First, it increases the amount of solute-free water reabsorbed back into the Circulatory system, circulation from the filtrate in the Nephron#Renal tubule, kidney tubules of the nephrons. Second, AVP constricts arterioles, which increases Vascular resistance, peripheral vascular resistance and raises arterial blood pressure. A third function is possible. Some AVP may be released directly into the brain from the hypothalamus, and may play an important role in social behavior, Sexual m ...
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Antihypotensive Agent
An antihypotensive agent, also known as a vasopressor agent or simply vasopressor, or pressor, is any substance, whether endogenous or a medication, that tends to raise low blood pressure. Some antihypotensive drugs act as vasoconstrictors to increase total peripheral resistance, others sensitize adrenoreceptors to catecholamines - glucocorticoids, and the third class increase cardiac output - dopamine, dobutamine. If low blood pressure is due to blood loss, then preparations increasing volume of blood circulation—plasma-substituting solutions such as colloid and crystalloid solutions (salt solutions)—will raise the blood pressure without any direct vasopressor activity. Packed red blood cells, plasma or whole blood should not be used solely for volume expansion or to increase oncotic pressure of circulating blood. Blood products should only be used if reduced oxygen carrying capacity or coagulopathy is present. Other causes of either absolute (dehydration, loss of plasma vi ...
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