Voacristine
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Voacristine
Voacristine is a indole alkaloid occurring in ''Voacanga'' and ''Tabernaemontana'' genus. It is also an iboga type alkaloid. Chemistry Its structure is almost similar to voacangine, an alkaloid used in semi-synthesis of ibogaine. Compared to voacangine, it has an extra O-atom. When it is degraded, iboxygaine and ibogaine are formed. Sources Voacristine is found in multiple species of ''Tabernaemontana'' some of which are Tabernaemontana divaricata, Tabernaemontana heyneana, Tabernaemontana ventricosa and in Voacanga africana. See also * Heyneanine * Voacamine * Vobasine Vobasine is a naturally occurring monoterpene indole alkaloid found in several species in the genus ''Tabernaemontana'' including ''Tabernaemontana divaricata''. History Vobasine was first reported by Renner in 1959 after its isolation from ''Voac ... References Tryptamine alkaloids {{Alkaloid-stub ...
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Tabernaemontana Divaricata
''Tabernaemontana divaricata'', commonly called pinwheel flower, crape jasmine, East India rosebay, and Nero's crown, is an evergreen shrub or small tree native to South Asia, Southeast Asia and China. In zones where it is not hardy it is grown as a house/glasshouse plant for its attractive flowers and foliage. The stem exudes a milky latex when broken, whence the name milk flower. Description The plant generally grows to a height of and is dichotomously branched. The large shiny leaves are deep green and about in length and in width. The waxy blossoms are found in small clusters on the stem tips. The (single) flowers have the characteristic 'pinwheel' shape also seen in other genera in the family Apocynaceae such as ''Vinca'' and ''Nerium''. Both single and double-flowered forms are cultivated, the flowers of both forms being white. The plant blooms in spring but flowers appear sporadically all year. The flowers have a pleasing fragrance. More than 66 alkaloids are found in ...
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Voacanga
''Voacanga'' is a genus of plants in the family Apocynaceae found in Africa, Southeast Asia, New Guinea, and Australia. the World Checklist of Selected Plant Families recognises 13 species:Search for "Voacanga", ;Species # ''Voacanga africana'' Stapf ex Scott-Elliot - tropical W + C + E + S Africa # ''Voacanga bracteata'' Stapf - tropical W + C Africa # ''Voacanga caudiflora'' Stapf - tropical W Africa # ''Voacanga chalotiana'' Pierre ex Stapf - tropical C Africa # ''Voacanga foetida'' ( Blume) Rolfe -Java, Borneo, Sumatra, Philippines # ''Voacanga globosa'' (Blanco) Merr. - Philippines # ''Voacanga gracilipes'' (Miq.) Markgr. - Maluku # ''Voacanga grandifolia'' (Miq.) Rolfe - Indonesia, Philippines, New Guinea, Queensland # ''Voacanga havilandii'' Ridl. - Sarawak # ''Voacanga megacarpa'' Merr. - Philippines # ''Voacanga pachyceras'' Leeuwenb. - Zaïre # ''Voacanga psilocalyx'' Pierre ex Stapf - Nigeria, Cameroon, Gabon, Republic of Congo # ''Voacanga thouarsii'' Roem. & S ...
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Planta Medica
''Planta Medica'' is a peer-reviewed journal published by Thieme Medical Publishers and covers medicinal plants and bioactive natural products of natural origin. ''Planta Medica'' is the official journal of the Society for Medicinal Plant and Natural Product Research (GA). According to the ''Journal Citation Reports'', the journal's 2016 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... is 2.342. Planta Medica is a Q1 journal in integrative and complementary medicine, and a Q2 journal in plant sciences. Oliver Kayser, from the TU Dortmund University, and Robert Fuerst, Wolfgang-von-Goethe University Frankfurt are the editors-in-chief. In the 18 issues published per year, Planta Medica covers the following areas of medicinal plants and natural product research: * B ...
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Voacamine
Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including ''Voacanga africana'' and ''Tabernaemontana divaricata''. It is approved for use as an antimalarial drug in several African countries. Voacamine exhibits cannabinoid CB1 receptor antagonistic activity. Chemistry Structure There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised. It has an ibogaine unit joined with vobasine unit. Adverse Effect Voacamine can cause hypertension in high dose. See also * Vincamine * Vobtusine Vobtusine is an alkaloid found in several different plants in the genus ''Voacanga ''Voacanga'' is a genus of plants in the family Apocynaceae found in Africa, Southeast Asia, New Guinea, and Australia. the World Checklist of Selected Plant Fa ... References {{R ...
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Heyneanine
Heyneanine is a ''Tabernaemontana'' alkaloid with ''in vitro'' antitumor activity. It also inhibits butrylcholinesterase. See also * Coronaridine * Voacangine Voacangine (12-methoxyibogamine-18-carboxylic acid methyl ester) is an alkaloid found predominantly in the root bark of the '' Voacanga africana'' tree, as well as in other plants such as ''Tabernanthe iboga'', '' Tabernaemontana africana'', ''Tra ... References Indole alkaloids Heterocyclic compounds with 5 rings {{alkaloid-stub ...
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Voacanga Africana
''Voacanga africana'' is a small tree native to tropical Africa belonging to the family Apocynaceae that grows to in height and bears leaves that are up to in length. The yellow or white flowers are succeeded by paired, follicular, dehiscent fruit with a mottled green exocarp and a pulpy, yellow mesocarp surrounding the seeds. The plant contains alkaloids acting as CNS depressants and hypotensives Description ''Voacanga africana'' is a small tree up to tall with a spreading crown. The leaves are in opposite pairs, dark glossy green above and paler green below. The white or yellow flowers are in small bunches borne either in leaf axils or at the end of shoots. The spherical, dark green fruits, dappled with paler green, grow usually in pairs and contain seeds embedded in a yellow pulp. History ''Voacanga africana'' was named by botanist Otto Stapf in 1894 after he received a type specimen from George Scott-Elliot, who had been participating in the Sierra Leone Boundary Commi ...
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Natural Product Research
''Natural Product Research'' is a peer-reviewed scientific journal covering research on natural products chemistry. It was established in 1992 by Atta ur Rahman (scientist), Atta-ur-Rahman. Abstracting and indexing

The journal is abstracted and indexed in *CAB Abstracts *Cambridge Crystallographic Data Centre *Chemical Abstracts Service *National Library of Medicine *PubMed *Science Citation Index Expanded *Scopus. Taylor & Francis academic journals English-language journals Chemistry journals {{chemistry-journal-stub ...
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Tabernaemontana Ventricosa
''Tabernaemontana ventricosa'' (commonly known as forest toad-tree or small-fruited toad-tree) is a plant in the family Apocynaceae. It grows as a shrub or small tree up to tall, with a trunk diameter of up to and has white sap. Leaves are paired (set opposite each other) and crowded near the ends of branches. They are oblong, leathery and a glossy dark green. Flowers are fragrant with white, somewhat twisted lobes, often with a pale yellow center and are set in small clusters at the ends of branches. The fruit is dark green, set in spreading pairs of ellipsoids or oval, beaked pods, up to in diameter. Its habitat is forests from sea level to altitude. In Zimbabwe, it is usually found as part of the understorey of evergreen forests. Local medicinal uses include the treatment of wounds, fever and hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently ele ...
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Journal Of Ethnopharmacology
The ''Journal of Ethnopharmacology'' is a peer-reviewed medical journal covering the traditional medicinal use of plants and other substances. It is the official journal of the International Society for Ethnopharmacology. The journal is included in the Index Medicus (MEDLINE MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...). References External links * International Society for Ethnopharmacology Pharmacology journals Elsevier academic journals Publications established in 1979 English-language journals {{ethno-stub ...
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Tabernaemontana Heyneana
''Tabernaemontana alternifolia'' is a species of plant in the family Apocynaceae. It is endemic to India. Taxonomy The name ''Tabernaemontana heyneana'' Wall. has often been used for this species, and a proposal was made to conserve that name so that it would be used instead of ''T. alternifolia''. Arguments made for conservation were that the type of the species was not a specimen but an illustration, and that the plant has opposite leaves In botany, phyllotaxis () or phyllotaxy is the arrangement of leaves on a plant stem. Phyllotactic spirals form a distinctive class of patterns in nature. Leaf arrangement The basic arrangements of leaves on a stem are opposite and alternat ..., not alternate leaves as ''alternifolia'' implies. However, the proposal was rejected, and the correct name of this species is the original name, ''T. alternifolia''. Image:Tabernaemontana alternifolia 26.JPG, Unripe fruit Image:Tabernaemontana alternifolia 21.JPG, Ripe fruit References * ...
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Tabernaemontana
''Tabernaemontana'' is a genus of flowering plants in the family Apocynaceae. It has a pan-tropical distribution, found in Asia, Africa, Australia, North America, South America, and a wide assortment of oceanic islands. These plants are evergreen shrubs and small trees growing to 1–15 m tall. The leaves are opposite, 3–25 cm long, with milky sap; hence it is one of the diverse plant genera commonly called "milkwood". The flowers are fragrant, white, 1–5 cm in diameter. The cultivar '' T. divaricata'' cv. 'Plena', with doubled-petaled flowers, is a popular houseplant. Some members of the genus ''Tabernaemontana'' are used as additives to some versions of the psychedelic drink ayahuasca; the genus is known to contain ibogaine (e.g. in bëcchëte, ''T. undulata''), conolidine (present in minor concentration in ''T. divaricata'') and voacangine ('' T. alba'', '' T. arborea'', '' T. africana''). Because of presence of coronaridine and voacangine in Mexican ''Tabernae ...
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Ibogaine
Ibogaine is a naturally occurring psychoactive substance found in plants in the family Apocynaceae such as ''Tabernanthe iboga'', ''Voacanga africana'', and ''Tabernaemontana undulata''. It is a psychedelic with dissociative properties. Preliminary research indicates that it may help counter drug addiction. Its use has been associated with serious side effects and death. Between the years 1990 and 2008, a total of 19 fatalities temporally associated with the ingestion of ibogaine were reported, from which six subjects died of acute heart failure or cardiopulmonary arrest. The total number of subjects who have used it without major side effects during this period remains unknown. It is used as an alternative medicine treatment for drug addiction in some countries. Its prohibition in other countries has slowed scientific research. Ibogaine is also used to facilitate psychological introspection and spiritual exploration. Various derivatives of ibogaine designed to lack psychedel ...
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