Titi Monkey Adenovirus
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Titi Monkey Adenovirus
Titi monkey adenovirus (TMAdV) is an adenovirus first identified in a New World titi monkey of the genus ''Callicebus'', and the virus also infected at least two humans. It is a large DNA-based virus which can cause death in monkeys, and respiratory illness has been recorded in humans. It was first discovered in Davis, California, at the California National Primate Research Center The California National Primate Research Center (CNPRC) is a federally funded biomedical research facility, dedicated to improving human and animal health, and located on the University of California, Davis, campus. The CNPRC is part of a network o .... The discovery of TMAdV was made by the laboratory of Charles Chiu and the UCSF-Abbott Viral Diagnostics and Discovery Center, using a DNA microarray test called the ViroChip that is able to detect all known as well as novel viruses. The virus is genetically different from any other adenovirus, and the origin or reservoir for TMAdV is still unknown. The ...
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Adenovirus
Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Virology Classification This family contains the following genera: * '' Atadenovirus'' * '' Aviadenovirus'' * '' Ichtadenovirus'' * '' Mastadenovirus'' (including all human adenoviruses) * '' Siadenovirus'' * '' Testadenovirus'' Diversity In humans, currently there are 88 human adenoviruses (HAdVs) in seven species (Human adenovirus A to G): * A: 12, 18, 31 * B: 3, 7, 11, 14, ...
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Titi Monkey
The titis, or titi monkeys, are New World monkeys of the subfamily Callicebinae, which contains three extant genera: ''Cheracebus'', ''Callicebus'', and ''Plecturocebus.'' This subfamily also contains the extinct genera ''Miocallicebus, Homunculus'', and ''Carlocebus''. Titi monkeys live in South America, from Colombia, Ecuador and Peru, east through Brazil, and south to Bolivia and northern Paraguay. Description Depending on species, titis have a head and body length of , and a tail, which is longer than the head and body, of . The different titi species vary substantially in coloring, but resemble each other in most other physical ways. They have long, soft fur, and it is usually reddish, brownish, grayish or blackish, and in most species the underside is lighter or more reddish than the upperside. Some species have contrasting blackish or whitish foreheads, while all members of the genus ''Cheracebus'' have a white half-collar. The tail is always furry and is not prehensile. ...
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PLOS Pathogens
''PLOS Pathogens'' is a peer-reviewed open-access medical journal. All content in ''PLOS Pathogens'' is published under the Creative Commons "by-attribution" license. ''PLOS Pathogens'' began operation in September 2005. It was the fifth journal of the Public Library of Science (PLOS), a non-profit open-access publisher. Journal Scope The journal scope of ''PLOS Pathogens'' is to feature ''PLOS Pathogens'' publishes original research and commentary that significantly advance the understanding of pathogens and how they interact with their host organisms. Topics include (but are not limited to) adaptive and innate immune defenses as well as pathogen countermeasures, emerging pathogens, evolution, genomics and gene regulation, model host organisms, pathogen-cell biology, pathogenesis, prions, proteomics and signal transduction, rational vaccine design, structural biology, and virulence factors. Content ''PLOS Pathogens'' publishes primary research articles, Pearls, Research M ...
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Davis, California
Davis is the most populous city in Yolo County, California. Located in the Sacramento Valley region of Northern California, the city had a population of 66,850 in 2020, not including the on-campus population of the University of California, Davis, which was over 9,400 (not including students' families) in 2016. there were 38,369 students enrolled at the university. History Davis sits on land that originally belonged to the Indigenous Patwin, a southern branch of Wintun people, who were killed or forced from their lands by the 1830s as part of the California Genocide through a combination of mass murders, smallpox and other diseases, and both Mexican and American systems of Indigenous slavery. Patwin burial grounds have been found across Davis, including on the site of the UC Davis Mondavi Center. After the killing and expulsion of the Patwin, territory that eventually became Davis emerged from one of California's most complicated, corrupt land grants, Laguna de Santos Callé ...
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California National Primate Research Center
The California National Primate Research Center (CNPRC) is a federally funded biomedical research facility, dedicated to improving human and animal health, and located on the University of California, Davis, campus. The CNPRC is part of a network of seven National Primate Research Centers developed to breed, house, care for and study primates for medical and behavioral research. Opened in 1962, researchers at this secure facility have investigated many diseases, ranging from asthma and Alzheimer's disease to AIDS and other infectious diseases, and has also produced discoveries about autism. CNPRC currently houses about 4,700 monkeys, the majority of which are rhesus macaques, with a small population of South American titi monkeys. The center, located on 300 acres (1.2 km2) 2.5 miles west of the UC Davis campus, is sponsored by the National Institutes of Health (NIH). Research program Scientists using the center's facilities produce numerous papers annually detailing their in ...
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Zoonosis
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in en ...
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List Of Primate Viruses
The following list of primate viruses is not exhaustive. Many viruses specific to non-human primates nevertheless are known to ''jump'' and infect humans and, thus, become known as zoonoses. {, class="wikitable" , - ! style="background:#ccf;", Simian virus name ! style="background:#ccf;", Primary host ! style="background:#ccf;", Human transmission case ! style="background:#ccf;", Severity in humans ! style="background:#ccf;", Severity in monkeys , - , Monkeypox virus ( Poxviridae ), , Monkeys , , Yes , , to 10% mortality (skin Rash), , Mild infection , - , Chimpanzee herpesvirus , , Chimp , , ?? , , ?? , , Latent infection , - , Langur herpesvirus , , Langur , , ?? , , ?? , , Latent infection , - , Lymphotrophic polyomavirus (LPV) , , Monkeys , , Yes (common) , , ?? , , ?? , - , Herpes B virus , , Macaque , , Yes (rare) , , High mortality rate, , Latent infection , - , Mason-Pfizer monkey virus ( Betaretrovirus ) (MPMV) , , Monkeys , , No , ...
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