Tropical Ulcer
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Tropical Ulcer
Tropical ulcer, more commonly known as jungle rot, is a chronic ulcerative skin lesion thought to be caused by polymicrobial infection with a variety of microorganisms, including mycobacteria. It is common in tropical climates. Ulcers occur on exposed parts of the body, primarily on anterolateral aspect of the lower limbs and may erode muscles and tendons, and sometimes, the bones.Medcyclopedia-Tropical ulcer These lesions may frequently develop on preexisting abrasions or sores sometimes beginning from a mere scratch. Signs and symptoms The vast majority of the tropical ulcers occur below the knee, usually around the ankle. They may also occur on arms. They are often initiated by minor trauma, and subjects with poor nutrition are at higher risk. Once developed, the ulcer may become chronic and stable, but also it can run a destructive course with deep tissue invasion, osteitis, and risk of amputation. Unlike Buruli ulcer, tropical ulcers are very painful. Lesions begin with i ...
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Goroka
Goroka is the capital of the Eastern Highlands Province of Papua New Guinea. It is a town of approximately 19,000 people (2000), above sea level. It has an airport (in the centre of town) and is on the " Highlands Highway", about 285 km from Lae in Morobe province and 90 km from the nearby town of Kainantu also in the Eastern Highlands. Other nearby towns include Kundiawa in Simbu Province and Mount Hagen in Western Highlands Province. It has a mild climate, known as a "perpetual Spring". It is the home of several national institutions: CRMF Christian Radio Missionary Fellowship, the PNG Institute of Medical Research, the National Film Institute, thLiturgical Catechetical Institute the Melanesian Institute, the Raun Raun Theatre Company and the University of Goroka. Several NGOs also have presences there, including Oxfam and Save the Children. The town's single largest hotel is the Bird of Paradise, owned by the Coral Seas Hotels chain. Coffee is a common cash cr ...
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Epithelioma
Epithelioma is an abnormal growth of the epithelium, which is the layer of tissue that covers the surfaces of organs and other structures of the body. Classification Epitheliomas can be benign growths or malignant carcinomas. They are classified according to the specific type of epithelial cells that are affected. The most common epitheliomas are basal cell carcinoma and squamous cell carcinoma (skin cancers). Treatment Treatment usually involves surgically removing the tumor and affected tissue. Also used is cryosurgery and radiotherapy. Prognosis The prognosis varies dramatically, depending on the type and stage at the time of treatment. However, the most common epitheliomas are very easily treated and rarely result in death. The condition did, however, take the life of Scottish golfer Willie Dunn, Sr. in 1878 at a time when the ailment was likely not fully understood. See also * Mule spinners' cancer Mule spinners' cancer or mule-spinners' cancer was a cancer, an epi ...
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Debridement
Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. Removal may be surgical, mechanical, chemical, autolytic (self-digestion), and by maggot therapy. In podiatry, practitioners such as chiropodists, podiatrists and foot health practitioners remove conditions such as calluses and verrucas. Debridement is an important part of the healing process for burns and other serious wounds; it is also used for treating some kinds of snake and spider bites. Sometimes the boundaries of the problem tissue may not be clearly defined. For example, when excising a tumor, there may be micrometastases along the edges of the tumor that are too small to be detected, but if not removed, could cause a relapse. In such circumstances, a surgeon may opt to debride a portion of the surrounding healthy tissue to ensure that the tumor is completely removed. Types There is lack of high quality evidence to compare th ...
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Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those with ...
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Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antiseptics) ...
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Footwear
Footwear refers to garments worn on the feet, which typically serves the purpose of protection against adversities of the environment such as wear from ground textures and temperature. Footwear in the manner of shoes therefore primarily serves the purpose to ease locomotion and prevent injuries. Footwear can also be used for fashion and adornment as well as to indicate the status or rank of the person within a social structure. Socks and other hosiery are typically worn additionally between the feet and other footwear for further comfort and relief. Cultures have different customs regarding footwear. These include not using any in some situations, usually bearing a symbolic meaning. This can however also be imposed on specific individuals to place them at a practical disadvantage against shod people, if they are excluded from having footwear available or are prohibited from using any. This usually takes place in situations of captivity, such as imprisonment or slavery, where the ...
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Streptococci
''Streptococcus'' is a genus of gram-positive ' (plural ) or spherical bacteria that belongs to the family Streptococcaceae, within the order Lactobacillales (lactic acid bacteria), in the phylum Bacillota. Cell division in streptococci occurs along a single axis, so as they grow, they tend to form pairs or chains that may appear bent or twisted. This differs from staphylococci, which divide along multiple axes, thereby generating irregular, grape-like clusters of cells. Most streptococci are oxidase-negative and catalase-negative, and many are facultative anaerobes (capable of growth both aerobically and anaerobically). The term was coined in 1877 by Viennese surgeon Albert Theodor Billroth (1829–1894), by combining the prefix "strepto-" (from ), together with the suffix "-coccus" (from Modern , from .) In 1984, many bacteria formerly grouped in the genus ''Streptococcus'' were separated out into the genera ''Enterococcus'' and ''Lactococcus''. Currently, over 50 specie ...
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Staphylococci
''Staphylococcus'' is a genus of Gram-positive bacteria in the family Staphylococcaceae from the order Bacillales. Under the microscope, they appear spherical (cocci), and form in grape-like clusters. ''Staphylococcus'' species are facultative anaerobic organisms (capable of growth both aerobically and anaerobically). The name was coined in 1880 by Scottish surgeon and bacteriologist Alexander Ogston (1844–1929), following the pattern established five years earlier with the naming of ''Streptococcus''. It combines the prefix "staphylo-" (from grc, σταφυλή, staphylē, bunch of grapes), and suffixed by the Modern (from ). Staphylococcus was one of the leading infections in hospitals and many strains of this bacterium have become antibiotic resistant. Despite strong attempts to get rid of them, staph bacteria stay present in hospitals, where they can infect people who are most at risk of infection. Staphylococcus includes at least 43 species. Of these, nine have two su ...
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Spirochaete
A spirochaete () or spirochete is a member of the phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm (double-membrane) gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or spiraled, hence the name) cells. Spirochaetes are chemoheterotrophic in nature, with lengths between 3 and 500 μm and diameters around 0.09 to at least 3 μm. Spirochaetes are distinguished from other bacterial phyla by the location of their flagella, called endoflagella which are sometimes called ''axial filaments''. Endoflagella are anchored at each end (pole) of the bacterium within the periplasmic space (between the inner and outer membranes) where they project backwards to extend the length of the cell. These cause a twisting motion which allows the spirochaete to move about. When reproducing, a spirochaete will undergo asexual transverse binary fission. Most spirochaetes are free-living and anaerobic, but there are numero ...
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Anaerobe
An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenated environment. Anaerobes may be unicellular (e.g. protozoans, bacteria) or multicellular. Most fungi are obligate aerobes, requiring oxygen to survive. However, some species, such as the Chytridiomycota that reside in the rumen of cattle, are obligate anaerobes; for these species, anaerobic respiration is used because oxygen will disrupt their metabolism or kill them. Deep waters of the ocean are a common anoxic environment. First observation In his letter of 14 June 1680 to The Royal Society, Antonie van Leeuwenhoek described an experiment he carried out by filling two identical glass tubes about halfway with crushed pepper powder, to which some clean rain water was added. Van Leeuwenhoek sealed one of the glass tubes using a flame and ...
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Bacillus Fusiformis
''Lysinibacillus fusiformis'' (commonly abbreviated ''L. fusiformis'') is a gram-positive, rod-shaped bacterium of the genus ''Lysinibacillus''.Priest, FG, M. Goodfellow, and C. Todd. "A Numerical Classification of the Genus Bacillus." National Center for Biotechnology Information. U.S. National Library of Medicine, July 1988. Web. 29 Apr. 2014. Scientists have yet to completely characterize this microbe's pathogenic nature.Smith, E. C. "Inoculation Experiments with Bacillus Fusiformis Isolated from Tropical Ulcer with Observations on the Bacillus." National Center for Biotechnology Information. U.S. National Library of Medicine, 14 Apr. 1933. Web. 29 Apr. 2014.Peters, William H. "Hand Infection Apparently Due to Bacillus Fusiformis."JSTOR. The Journal of Infectious Diseases, 15 June 1911. Web. 29 Apr. 2014. Though little is known about this organism, several genome sequencing projects for various strains of ''L. fusiformis'' are currently underway."Lysinibacillus Fusiformis." Nati ...
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Mycobacterium Ulcerans
''Mycobacterium ulcerans'' is a species of bacteria found in various aquatic environments. The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer. ''M. ulcerans'' is closely related to ''Mycobacterium marinum'', from which it evolved around one million years ago, and more distantly to the mycobacteria which cause tuberculosis and leprosy. Description ''M. ulcerans'' are rod-shaped bacteria. They appear purple ("Gram positive") under Gram stain and bright red ("acid fast") under Ziehl–Neelsen stain. On laboratory media, ''M. ulcerans'' grow slowly, forming small transparent colonies after four weeks. As colonies age, they develop irregular outlines and a rough, yellow surface. Taxonomy and evolution ''M. ulcerans'' is a species of mycobacteria within the phylum Actinomycetota. Within the genus ''Mycobacterium'', ''M. ulcerans'' is classified as both a "non-tuberculous mycobacterium" and a "slow-growing mycobacterium". ''M. ...
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