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Tetrahydrozoline
Tetryzoline (also known as tetrahydrozoline) is a drug used in some over-the-counter eye drops and nasal sprays. Tetryzoline was patented in 1954, and came into medical use in 1959. Side effects Tetryzoline eye drops may cause blurred vision, eye irritation and dilated pupils. Tetryzoline is not suitable for prolonged use as its vasoconstrictive effects within the eye eventually decrease or stop. If tolerance to the drug has developed, ceasing its use may cause a rebound effect and ''increase'' redness of the eyes — a vasodilatory effect. Intranasal use of tetryzoline may cause transient burning, stinging, or dryness of the mucosa and sneezing. Prolonged intranasal use often causes opposite effects in the form of rebound congestion with effects such as chronic redness, swelling and rhinitis. Prolonged use thus may result in overuse of the drug. In children, it might cause profound sedation. Overdose Overdose most often causes slow heart rate. Respiratory depression, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visine
Visine is a brand of eye drops produced by Johnson & Johnson. Johnson & Johnson acquired Visine, along with Pfizer's entire consumer healthcare portfolio, in December 2006. In some countries it is called Vispring. Visine Original The active ingredients in the original Visine formulation are potassium chloride and tetrahydrozoline hydrochloride which is a vasoconstrictor, and therefore constricts the eye's superficial blood vessels. Administration Visine is administered topically with 1 to 2 drops applied to the affected eye(s) up to 4 times daily. Adverse effects *Those using Visine Original frequently report stinging and burning upon application. *Use of this product can cause a rebound effect causing the redness to worsen. Prolonged use can cause blood vessels to be dilated for an extended period of time. Use should be limited unless specified by a doctor. *A red eye may often be indicative of more serious underlying ocular condition; simply reducing blood flow to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha-1 Receptor
alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein. α1-adrenergic receptors are subdivided into three highly homologous subtypes, i.e., α1A-, α1B-, and α1D-adrenergic receptor subtypes. There is no α1C receptor. At one time, there was a subtype known as α1C, but it was found to be identical to the previously discovered α1A receptor subtype. To avoid confusion, naming was continued with the letter D. Catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) signal through the α1-adrenergic receptors in the central and peripheral nervous systems. The crystal structure of the α1B-adrenergic receptor subtype has been determined in complex with the inverse agonist (+)-cyclazosin. Effects The α1-adrenergic receptor has several general functions in common with the α2-adrenergic receptor, but also has specific effects of its own. α1-receptors primarily mediate smooth muscle co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eye Drop
Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation such as itching or redness. Eye drops may also contain one or more medications to treat a wide variety of eye diseases. Depending on the condition being treated, they may contain steroids, antihistamines, sympathomimetics, beta receptor blockers, parasympathomimetics, parasympatholytics, prostaglandins, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, antifungals, or topical anesthetics. Eye drops have less of a risk of side effects than do oral medicines, and such risk can be minimized by occluding the lacrimal punctum (i.e. pressing on the inner corner of the eye) for a short while after instilling drops. Prior to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
North Carolina
North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and South Carolina to the south, and Tennessee to the west. In the 2020 census, the state had a population of 10,439,388. Raleigh is the state's capital and Charlotte is its largest city. The Charlotte metropolitan area, with a population of 2,595,027 in 2020, is the most-populous metropolitan area in North Carolina, the 21st-most populous in the United States, and the largest banking center in the nation after New York City. The Raleigh-Durham-Cary combined statistical area is the second-largest metropolitan area in the state and 32nd-most populous in the United States, with a population of 2,043,867 in 2020, and is home to the largest research park in the United States, Research Triangle Park. The earliest evidence of human occupation i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pewaukee, Wisconsin
Pewaukee is a city in Waukesha County, Wisconsin. The population was 13,195 at the 2010 census. The Village of Pewaukee, which was incorporated out of the town before it incorporated as a city, is surrounded by the city. The name of the city of Pewaukee comes from that of the name of the village, which is rather unclear in itself. Many names are given as to the etymology of the name. History The city of Pewaukee was incorporated in 1999, from the parts of the former Town of Pewaukee not included in the Village of Pewaukee. The town had been established by an act of the Wisconsin Territorial Legislature approved January 13, 1840, eight years before Wisconsin gained statehood. When voting took place to decide the county seat for Waukesha County, Waukesha beat out Pewaukee by two votes. At the time, Governor Tyler Novak represented Pewaukee in court. The Chicago, Milwaukee, St. Paul and Pacific Railroad (Milwaukee Road) constructed a railroad line through Pewaukee in 1855, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Date Rape Drug
A date rape drug is any drug that incapacitates another person and renders that person vulnerable to sexual assault, including rape. The substances are associated with date rape because of reported incidents of their use in the context of two people dating, during which the victim is sexually assaulted or raped or suffers other harm. However, substances have also been exploited during retreats, for example ayahuasca retreats. The substances are not exclusively used to perpetrate sexual assault or rape, but are the properties or side-effects of substances normally used for legitimate medical purposes. One of the most common incapacitating agents for date rape is alcohol, administered either surreptitiously or consumed voluntarily,Alcohol Is Most Common 'Date Rape' Drug . Medicalnewstoday.com. Retrieved on June 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Carolina
)''Animis opibusque parati'' ( for, , Latin, Prepared in mind and resources, links=no) , anthem = " Carolina";" South Carolina On My Mind" , Former = Province of South Carolina , seat = Columbia , LargestCity = Charleston , LargestMetro = Greenville (combined and metro) Columbia (urban) , BorderingStates = Georgia, North Carolina , OfficialLang = English , population_demonym = South Carolinian , Governor = , Lieutenant Governor = , Legislature = General Assembly , Upperhouse = Senate , Lowerhouse = House of Representatives , Judiciary = South Carolina Supreme Court , Senators = , Representative = 6 Republicans1 Democrat , postal_code = SC , TradAbbreviation = S.C. , area_rank = 40th , area_total_sq_mi = 32,020 , area_total_km2 = 82,932 , area_land_sq_mi = 30,109 , area_land_km2 = 77,982 , area_water_sq_mi = 1,911 , area_water_km2 = 4,949 , area_water_percent = 6 , population_rank = 23rd , population_as_of = 2022 , 2010Pop = 5282634 , population ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urban Legend
An urban legend (sometimes contemporary legend, modern legend, urban myth, or urban tale) is a genre of folklore comprising stories or fallacious claims circulated as true, especially as having happened to a "friend of a friend" or a family member, often with horrifying, humorous, or cautionary elements. These legends can be entertaining but often concern mysterious peril or troubling events, such as disappearances and strange objects or entities. Urban legends may confirm moral standards, reflect prejudices, or be a way to make sense of societal anxieties. Urban legends in the past were most often circulated orally, but now can also be spread by any media. This includes newspapers, mobile news apps, e-mail, and most often, social media. Some urban legends have passed through the years/decades with only minor changes, in where the time period takes place. Generic urban legends are often altered to suit regional variations, but the lesson or moral remains majorly the same. Or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enantiomers
In chemistry, an enantiomer ( /ɪˈnænti.əmər, ɛ-, -oʊ-/ ''ih-NAN-tee-ə-mər''; from Ancient Greek ἐνάντιος ''(enántios)'' 'opposite', and μέρος ''(méros)'' 'part') – also called optical isomer, antipode, or optical antipode – is one of two stereoisomers that are non-superposable onto their own mirror image. Enantiomers are much like one's right and left hands, when looking at the same face, they cannot be superposed onto each other. No amount of reorientation will allow the four unique groups on the chiral carbon (see Chirality (chemistry)) to line up exactly. The number of stereoisomers a molecule has can be determined by the number of chiral carbons it has. Stereoisomers include both enantiomers and diastereomers. Diastereomers, like enantiomers, share the same molecular formula and are non-superposable onto each other however, they are not mirror images of each other. A molecule with chirality rotates plane-polarized light. A mixture of equals amou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction. In the past, derivative also meant a compound that ''can be imagined to'' arise from another compound, if one atom or group of atoms is replaced with another atom or group of atoms, but modern chemical language now uses the term structural analog for this meaning, thus eliminating ambiguity. The term "structural analogue" is common in organic chemistry. In biochemistry, the word is used for compounds that at least theoretically can be formed from the precursor compound. Chemical derivatives may be used to facilitate analysis. For example, melting point (MP) analysis can assist in identification of many organic compounds. A crystalline derivative may be prepared, such as a semicarbazone or 2,4-dinitrophenylhydrazone (derived from aldehydes or ketones), as a simple way of verifying the identity of the original compound, assuming that a table of derivative MP values is available ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
