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Stratum Lucidum Of Hippocampus
The stratum lucidum of the hippocampus is a layer of the hippocampus between the stratum pyramidale and the stratum radiatum. It is the tract of the mossy fiber projections, both inhibitory and excitatory from the granule cells of the dentate gyrus. One mossy fiber may make up to 37 connections to a single pyramidal cell, and innervate around 12 pyramidal cells on top of that. Any given pyramidal cell in the stratum lucidum may get input from as many as 50 granule cells. Location The stratum lucidum is located within the CA3 region of the hippocampus distally to the dentate gyrus and proximally to the CA2 region. It is composed of a densely packed bundle of mossy fibers (unmyelinated) and spiny and aspiny interneurons that lie immediately above the CA3 pyramidal cell layer in the hippocampus, and immediately below the stratum radiatum. Most mossy fiber axons are perpendicular to the CA3 pyramidal region where they project and synapse to either the CA3 pyramidal cells or the stra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus
The hippocampus (via Latin from Greek , 'seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located in the allocortex, with neural projections into the neocortex in humans, as well as primates. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In humans, it contains two main interlocking parts: the hippocampus proper (also called ''Ammon's horn''), and the dentate gyrus. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; short-term memory loss and disorientation are included among the early symptoms. Damage to the hippocampus can also result from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stratum Pyramidale
In geology and related fields, a stratum ( : strata) is a layer of rock or sediment characterized by certain lithologic properties or attributes that distinguish it from adjacent layers from which it is separated by visible surfaces known as either '' bedding surfaces'' or ''bedding planes''.Salvador, A. ed., 1994. ''International stratigraphic guide: a guide to stratigraphic classification, terminology, and procedure. 2nd ed.'' Boulder, Colorado, The Geological Society of America, Inc., 215 pp. . Prior to the publication of the International Stratigraphic Guide, older publications have defined a stratum as either being either equivalent to a single bed or composed of a number of beds; as a layer greater than 1 cm in thickness and constituting a part of a bed; or a general term that includes both ''bed'' and ''lamina''.Neuendorf, K.K.E., Mehl, Jr., J.P., and Jackson, J.A. , eds., 2005. ''Glossary of Geology'' 5th ed. Alexandria, Virginia, American Geological Institute. 779 pp. . ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stratum Radiatum
In geology and related fields, a stratum ( : strata) is a layer of rock or sediment characterized by certain lithologic properties or attributes that distinguish it from adjacent layers from which it is separated by visible surfaces known as either '' bedding surfaces'' or ''bedding planes''.Salvador, A. ed., 1994. ''International stratigraphic guide: a guide to stratigraphic classification, terminology, and procedure. 2nd ed.'' Boulder, Colorado, The Geological Society of America, Inc., 215 pp. . Prior to the publication of the International Stratigraphic Guide, older publications have defined a stratum as either being either equivalent to a single bed or composed of a number of beds; as a layer greater than 1 cm in thickness and constituting a part of a bed; or a general term that includes both ''bed'' and ''lamina''.Neuendorf, K.K.E., Mehl, Jr., J.P., and Jackson, J.A. , eds., 2005. ''Glossary of Geology'' 5th ed. Alexandria, Virginia, American Geological Institute. 779 pp. . ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dentate Gyrus
The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum. The dentate gyrus is part of the hippocampal trisynaptic circuit and is thought to contribute to the formation of new episodic memories, the spontaneous exploration of novel environments and other functions. It is notable as being one of a select few brain structures known to have significant rates of adult neurogenesis in many species of mammals, from rodents to primates. Other sites of adult neurogenesis include the subventricular zone, the striatum and the cerebellum. However, whether significant neurogenesis exists in the adult human dentate gyrus has been a matter of debate. 2019 evidence has shown that adult neurogenesis does take place in the subventricular zone and in the subgranular zone of the dentate gyrus. Structure The dentate gyrus, like the hippocampus, consists of three distinct layers: an outer molecular layer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus Anatomy
Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of the brain. It has a distinctive, curved shape that has been likened to the sea-horse monster of Greek mythology and the ram's horns of Amun in Egyptian mythology. This general layout holds across the full range of mammalian species, from hedgehog to human, although the details vary. For example, in the rat, the two hippocampi look similar to a pair of bananas, joined at the stems. In primate brains, including humans, the portion of the hippocampus near the base of the temporal lobe is much broader than the part at the top. Due to the three-dimensional curvature of this structure, two-dimensional sections such as shown are commonly seen. Neuroimaging pictures can show a number of different shapes, depending on the angle and location of the cut. Topologically, the surface of a cerebral hemisphere can be regarded as a sphere with an indentat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Bodies
The soma (pl. ''somata'' or ''somas''), perikaryon (pl. ''perikarya''), neurocyton, or cell body is the bulbous, non-process portion of a neuron or other brain cell type, containing the cell nucleus. The word 'soma' comes from the Greek '' σῶμα'', meaning 'body'. Although it is often used to refer to neurons, it can also refer to other cell types as well, including astrocytes, oligodendrocytes, and microglia. There are many different specialized types of neurons, and their sizes vary from as small as about 5 micrometres to over 10 millimetres for some of the smallest and largest neurons of invertebrates, respectively. The soma of a neuron (i.e., the main part of the neuron in which the dendrites branch off of) contains many organelles, including granules called Nissl granules, which are composed largely of rough endoplasmic reticulum and free polyribosomes. The cell nucleus is a key feature of the soma. The nucleus is the source of most of the RNA that is produced in neu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyramidal Neuron
Pyramidal cells, or pyramidal neurons, are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal neurons are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract. Pyramidal neurons are also one of two cell types where the characteristic sign, Negri bodies, are found in post-mortem rabies infection. Pyramidal neurons were first discovered and studied by Santiago Ramón y Cajal. Since then, studies on pyramidal neurons have focused on topics ranging from neuroplasticity to cognition. Structure File:GFPneuron.png, Pyramidal neuron visualized by green fluorescent protein (gfp) File:Hippocampal-pyramidal-cell.png, A hippocampal pyramidal cell One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named. Other key structural features of the pyramidal cell are a single axon, a large apical dendrite, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Excitatory Neuron
An excitatory synapse is a synapse in which an action potential in a presynaptic neuron increases the probability of an action potential occurring in a postsynaptic cell. Neurons form networks through which nerve impulses travel, each neuron often making numerous connections with other cells. These electrical signals may be excitatory or inhibitory, and, if the total of excitatory influences exceeds that of the inhibitory influences, the neuron will generate a new action potential at its axon hillock, thus transmitting the information to yet another cell. This phenomenon is known as an excitatory postsynaptic potential (EPSP). It may occur via direct contact between cells (i.e., via gap junctions), as in an electrical synapse, but most commonly occurs via the vesicular release of neurotransmitters from the presynaptic axon terminal into the synaptic cleft, as in a chemical synapse. The excitatory neurotransmitters, the most common of which is glutamate, then migrate via d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interneurons
Interneurons (also called internuncial neurons, relay neurons, association neurons, connector neurons, intermediate neurons or local circuit neurons) are neurons that connect two brain regions, i.e. not direct motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits, enabling communication between sensory or motor neurons and the central nervous system (CNS). They play vital roles in reflexes, neuronal oscillations, and neurogenesis in the adult mammalian brain. Interneurons can be further broken down into two groups: local interneurons and relay interneurons. Local interneurons have short axons and form circuits with nearby neurons to analyze small pieces of information. Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions. However, interneurons are generally considered to operate mainly within local brain areas. The interaction between interneurons allow the brain to perform compl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Axon
An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function of the axon is to transmit information to different neurons, muscles, and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the axons are called afferent nerve fibers and the electrical impulse travels along these from the periphery to the cell body and from the cell body to the spinal cord along another branch of the same axon. Axon dysfunction can be the cause of many inherited and acquired neurological disorders that affect both the peripheral and central neurons. Nerve fibers are classed into three typesgroup A nerve fibers, group B nerve fibers, and group C nerve fibers. Groups A and B are myelinated, and group C are unmyelinated. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
