Spirapril
Spirapril, sold under the brand name Renormax among others, is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors. It was patented in 1980 and approved for medical use in 1995. Chemistry Like many ACE inhibitors, this prodrug is converted to the active metabolite spiraprilat following oral administration. Unlike other members of the group, it is eliminated both by renal and hepatic routes, which may allow for greater use in patients with renal impairment. However, data on its effect upon the renal function Assessment of kidney function occurs in different ways, using the presence of symptoms and signs, as well as measurements using urine tests, blood tests, and medical imaging. Functions of a healthy kidney include maintaining a person's fluid ... are conflicting. References External links * ACE inhibitors Carboxamides Enantiopure drugs Ethyl esters Nitrogen heterocycles Prodrugs Spiro compoun ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]