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Spike Sorting
Spike sorting is a class of techniques used in the analysis of electrophysiological data. Spike sorting algorithms use the shape(s) of waveforms collected with one or more electrodes in the brain to distinguish the activity of one or more neurons from background electrical noise. Neurons produce action potentials that are referred to as 'spikes' in laboratory jargon. Frequently this term is used for electrical signals recorded in the vicinity of individual neurons with a microelectrode (exception: 'spikes' in EEG recordings). In these recordings action potentials appear as sharp spikes (deviations from the baseline). These extracellular electrodes pick up all the components constituting the field at the point of its contact. This includes the component due to the synaptic currents and the action potentials. The synaptic currents have slower time course and the spikes have faster time course. They are thus easily separated by filtering: highpass for spikes and low pass for the syn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophysiology
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , '' -logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biologi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sorting Algorithm
In computer science, a sorting algorithm is an algorithm that puts elements of a List (computing), list into an Total order, order. The most frequently used orders are numerical order and lexicographical order, and either ascending or descending. Efficient sorting is important for optimizing the Algorithmic efficiency, efficiency of other algorithms (such as search algorithm, search and merge algorithm, merge algorithms) that require input data to be in sorted lists. Sorting is also often useful for Canonicalization, canonicalizing data and for producing human-readable output. Formally, the output of any sorting algorithm must satisfy two conditions: # The output is in monotonic order (each element is no smaller/larger than the previous element, according to the required order). # The output is a permutation (a reordering, yet retaining all of the original elements) of the input. For optimum efficiency, the input data should be stored in a data structure which allows random access ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spike Sorting, Christophe Pouzat, NeuroMat-vSydfDvsewY
Spike, spikes, or spiking may refer to: Arts, entertainment, and media Books * ''The Spike'' (novel), a novel by Arnaud de Borchgrave * ''The Spike'' (book), a nonfiction book by Damien Broderick * ''The Spike'', a starship in Peter F. Hamilton's ''The Evolutionary Void'' Comics * ''Spike'' (DC Thomson) a British comics anthology published by DC Thomson * ''Spike'' (IDW Publishing), a comic book series featuring the ''Buffy the Vampire Slayer'' character Film and television * ''Spike'' (2008 film), directed by Robert Beaucage * Spike (dog), a dog actor * Spike (TV channel), a former name of the American cable network Paramount Network **5Spike, a former localized British version of the American channel ** Spike (Australian TV channel), a localized version of the American channel ** Spike (Dutch TV channel), a localized version of the American channel * "Spike!", a segment of the 2017 Thai TV series '' Project S: The Series'' Music * ''Spike'' (Agata album), 2004 * ''Spi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Action Potentials
An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and in some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell-cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward synaptic boutons situated at the ends of an axon; these signals can then connect with other neurons at synapses, or to motor cells or glands. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leadi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microelectrode
A microelectrode is an electrode used in electrophysiology either for recording neural signals or for the electrical stimulation of nervous tissue (they were first developed by Ida Hyde in 1921). Pulled glass pipettes with tip diameters of 0.5 μm or less are usually filled with 3 molars potassium chloride solution as the electrical conductor. When the tip penetrates a cell membrane the lipids in the membrane seal onto the glass, providing an excellent electrical connection between the tip and the interior of the cell, which is apparent because the microelectrode becomes electrically negative compared to the extracellular solution. There are also microelectrodes made with insulated metal wires, made from inert metals with high Young modulus such as tungsten, stainless steel, or platinum-iridium alloy and coated with glass or polymer insulator with exposed conductive tips. These are mostly used for recording from the external side of the cell membrane. More recent advances i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Local Field Potential
Local field potentials (LFP) are transient electrical signals generated in nervous and other tissues by the summed and synchronous electrical activity of the individual cells (e.g. neurons) in that tissue. LFP are "extracellular" signals, meaning that they are generated by transient imbalances in ion concentrations in the spaces outside the cells, that result from cellular electrical activity. LFP are 'local' because they are recorded by an electrode placed nearby the generating cells. As a result of the Inverse-square law, such electrodes can only 'see' potentials in spatially limited radius. They are 'potentials' because they are generated by the voltage that results from charge separation in the extracellular space. They are 'field' because those extracellular charge separations essentially create a local electric field. LFP are typically recorded with a high-impedance microelectrode placed in the midst of the population of cells generating it. They can be recorded, for exam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Principal Components Analysis
Principal component analysis (PCA) is a popular technique for analyzing large datasets containing a high number of dimensions/features per observation, increasing the interpretability of data while preserving the maximum amount of information, and enabling the visualization of multidimensional data. Formally, PCA is a statistical technique for reducing the dimensionality of a dataset. This is accomplished by linearly transforming the data into a new coordinate system where (most of) the variation in the data can be described with fewer dimensions than the initial data. Many studies use the first two principal components in order to plot the data in two dimensions and to visually identify clusters of closely related data points. Principal component analysis has applications in many fields such as population genetics, microbiome studies, and atmospheric science. The principal components of a collection of points in a real coordinate space are a sequence of p unit vectors, where the i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wavelet Analysis
A wavelet is a wave-like oscillation with an amplitude that begins at zero, increases or decreases, and then returns to zero one or more times. Wavelets are termed a "brief oscillation". A taxonomy of wavelets has been established, based on the number and direction of its pulses. Wavelets are imbued with specific properties that make them useful for signal processing. For example, a wavelet could be created to have a frequency of Middle C and a short duration of roughly one tenth of a second. If this wavelet were to be convolved with a signal created from the recording of a melody, then the resulting signal would be useful for determining when the Middle C note appeared in the song. Mathematically, a wavelet correlates with a signal if a portion of the signal is similar. Correlation is at the core of many practical wavelet applications. As a mathematical tool, wavelets can be used to extract information from many different kinds of data, including but not limited to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetrode
A tetrode is a vacuum tube (called ''valve'' in British English) having four active electrodes. The four electrodes in order from the centre are: a thermionic cathode, first and second grids and a plate (called ''anode'' in British English). There are several varieties of tetrodes, the most common being the screen-grid tube and the beam tetrode. In screen-grid tubes and beam tetrodes, the first grid is the control grid and the second grid is the screen grid. In other tetrodes one of the grids is a control grid, while the other may have a variety of functions. The tetrode was developed in the 1920s by adding an additional grid to the first amplifying vacuum tube, the triode, to correct limitations of the triode. During the period 1913 to 1927, three distinct types of tetrode valves appeared. All had a normal control grid whose function was to act as a primary control for current passing through the tube, but they differed according to the intended function of the other grid. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Printed Circuit Board
A printed circuit board (PCB; also printed wiring board or PWB) is a medium used in Electrical engineering, electrical and electronic engineering to connect electronic components to one another in a controlled manner. It takes the form of a Lamination, laminated sandwich structure of conductive and insulating layers: each of the conductive layers is designed with an artwork pattern of traces, planes and other features (similar to wires on a flat surface) Chemical milling, etched from one or more sheet layers of copper Lamination, laminated onto and/or between sheet layers of a Insulator (electricity), non-conductive substrate. Electrical components may be fixed to conductive pads on the outer layers in the shape designed to accept the component's terminals, generally by means of soldering, to both electrically connect and mechanically fasten them to it. Another manufacturing process adds Via (electronics), vias: plated-through holes that allow interconnections between layers. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spike Clusters
Spike, spikes, or spiking may refer to: Arts, entertainment, and media Books * ''The Spike'' (novel), a novel by Arnaud de Borchgrave * ''The Spike'' (book), a nonfiction book by Damien Broderick * ''The Spike'', a starship in Peter F. Hamilton's ''The Evolutionary Void'' Comics * ''Spike'' (DC Thomson) a British comics anthology published by DC Thomson * ''Spike'' (IDW Publishing), a comic book series featuring the ''Buffy the Vampire Slayer'' character Film and television * ''Spike'' (2008 film), directed by Robert Beaucage * Spike (dog), a dog actor * Spike (TV channel), a former name of the American cable network Paramount Network **5Spike, a former localized British version of the American channel ** Spike (Australian TV channel), a localized version of the American channel ** Spike (Dutch TV channel), a localized version of the American channel * "Spike!", a segment of the 2017 Thai TV series '' Project S: The Series'' Music * ''Spike'' (Agata album), 2004 * ''Spi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
