Sparaganosis
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Sparaganosis
Sparganosis is a parasitic infection caused by the plerocercoid larvae of the genus ''Spirometra'' including ''S. mansoni'', ''S. ranarum'', ''S. mansonoides'' and ''S. erinacei''.John, D.T. and Petri, W.A. Markell and Voge's Medical Parasitology. 9th edition. St. Louis: Saunders Elsevier, 2006. It was first described by Patrick Manson from China in 1882, and the first human case was reported by Charles Wardell Stiles from Florida in 1908. The infection is transmitted by ingestion of contaminated water, ingestion of a second intermediate host such as a frog or snake, or contact between a second intermediate host and an open wound or mucous membrane.Manson, P., Manson-Bahr, P., and Wilcocks, C. Manson's Tropical Diseases: A Manual of the Diseases. New York: William Wood and Company, 1921. Humans are the accidental hosts in the life cycle, while dogs, cats, and other mammals are definitive hosts. Copepods (freshwater crustaceans) are the first intermediate hosts, and various amphib ...
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Parasite
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the host's body ...
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Brain Abscess
Brain abscess (or cerebral abscess) is an abscess caused by inflammation and collection of infected material, coming from local (ear infection, dental abscess, infection of paranasal sinuses, infection of the mastoid air cells of the temporal bone, epidural abscess) or remote ( lung, heart, kidney etc.) infectious sources, within the brain tissue. The infection may also be introduced through a skull fracture following a head trauma or surgical procedures. Brain abscess is usually associated with congenital heart disease in young children. It may occur at any age but is most frequent in the third decade of life. Signs and symptoms Fever, headache, and neurological problems, while classic, only occur in 20% of people with brain abscess. The famous triad of fever, headache and focal neurologic findings are highly suggestive of brain abscess. These symptoms are caused by a combination of increased intracranial pressure due to a space-occupying lesion (headache, vomiting, confusion ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequen ...
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ELISA
The enzyme-linked immunosorbent assay (ELISA) (, ) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971. The assay uses a solid-phase type of enzyme immunoassay (EIA) to detect the presence of a ligand (commonly a protein) in a liquid sample using antibodies directed against the protein to be measured. ELISA has been used as a diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries. In the most simple form of an ELISA, antigens from the sample to be tested are attached to a surface. Then, a matching antibody is applied over the surface so it can bind the antigen. This antibody is linked to an enzyme and then any unbound antibodies are removed. In the final step, a substance containing the enzyme's substrate is added. If there was binding, the subsequent reaction produces a detectable signal, most commonly a color change. Performing an ELISA involves at le ...
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Procercoid
Procercoid is the first larval stage of some tapeworms, which usually develops inside the body cavity of copepods. Flatworm in this stage is not enclosed in a protective cyst, but is infectious. Procercoids resemble their adult forms in pathways of energy metabolism. They are basically anaerobic, lacking complete Krebs Cycle, and rely on glycolysis Glycolysis is the metabolic pathway that converts glucose () into pyruvate (). The free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH .... References {{reflist Larvae ...
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Cyclops (genus)
''Cyclops'' is one of the most common genera of freshwater copepods, comprising over 400 species. Together with other similar-sized non-copepod fresh-water crustaceans, especially cladocera, they are commonly called ''water fleas''. The name ''Cyclops'' comes from the Cyclops of Greek mythology, as they have a single large eye; in ''Cyclops'', the eye may be either red or black. Anatomy ''Cyclops'' individuals may range from ½–5 mm long and are clearly divided into two sections. The broadly oval front section comprises the head and the first five thoracic segments. The hind part is considerably slimmer and is made up of the sixth thoracic segment and the four legless pleonic segments. Two caudal appendages project from the rear. Although they may be difficult to observe, ''Cyclops'' has 5 pairs of legs. The long first antennae, 2 in number, are used by the males for gripping the females during mating. Afterwards, the female carries the eggs in two small sacs on h ...
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Small Intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called intestinal villus, villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitamin B12, vita ...
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Scolex
Cestoda is a class of parasitic worms in the flatworm phylum (Platyhelminthes). Most of the species—and the best-known—are those in the subclass Eucestoda; they are ribbon-like worms as adults, known as tapeworms. Their bodies consist of many similar units known as proglottids—essentially packages of eggs which are regularly shed into the environment to infect other organisms. Species of the other subclass, Cestodaria, are mainly fish infecting parasites. All cestodes are parasitic; many have complex life histories, including a stage in a definitive (main) host in which the adults grow and reproduce, often for years, and one or two intermediate stages in which the larvae develop in other hosts. Typically the adults live in the digestive tracts of vertebrates, while the larvae often live in the bodies of other animals, either vertebrates or invertebrates. For example, ''Diphyllobothrium'' has at least two intermediate hosts, a crustacean and then one or more freshwater ...
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Poultice
A poultice, also called a cataplasm, is a soft moist mass, often heated and medicated, that is spread on cloth and placed over the skin to treat an aching, inflamed, or painful part of the body. It can be used on wounds, such as cuts. 'Poultice' may also refer to a porous solid filled with a solvent used to remove stains from porous stone such as marble or granite. The word "poultice" comes from the Greek word "poltos" transformed in the Latin ''puls, pultes'', meaning "porridge". Types * Some Native Americans used mashed pumpkin or devil’s club as a poultice. *Native Americans have thousands of plants for the making of poultices. The known tribes who utilize(d) plants for poultices include the Abnaki, Aleut, some Algonquin bands, Anticosti, some Apache tribes, Atsugewi, Bella Coola, Blackfoot, Cahuilla, California Indian, Carrier bands, Catawba, Chehalis, Cherokee, some Cheyenne, Chickasaw, Chippewa, Choctaw, Clallam, Coahuilla, some Cocopa, Comanche, Con ...
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Biopsy
A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is then fixed, dehydrated, embedded, sectioned, stained and mounted before it is generally examined under a microscope by a pathologist; it may also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. An incisional biopsy or core biopsy samples a portion of the abnormal tissue without attempting to remove the entire lesion or tumor. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous or inflammatory conditions. Histor ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and ...
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Spirometra Erinaceieuropaei
''Spirometra erinaceieuropaei'' is a parasitic tapeworm that infects domestic animals and humans. The medical term for this infection in humans and other animals is sparganosis. Morphologically, these worms are similar to other worms in the genus ''Spirometra''. They have a long body consisting of three sections: the scolex, the neck, and the strobilia. They have a complex life cycle that consists of three hosts, and can live in varying environments and bodily tissues. Humans can contract this parasite in three main ways (ingestion of under cooked meat, contaminated water, or poultices contained contaminated flesh). Historically, humans are considered a paratenic host; however, the first case of an adult ''S. erinaceieuropaei'' infection in humans was reported in 2017. ''Spirometra'' tapeworms exist worldwide and infection is common in animals, but ''S. erinaceieuropaei'' infections are rare in humans. Treatment for infection typically includes surgical removal and anti-worm medica ...
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