Sinoatrial Node
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Sinoatrial Node
The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately fifteen mm long, three mm wide, and one mm thick, located directly below and to the side of the superior vena cava. These cells can produce an electrical impulse an action potential known as a cardiac action potential that travels through the electrical conduction system of the heart, causing it to contract. In a healthy heart, the SA node continuously produces action potentials, setting the rhythm of the heart (sinus rhythm), and so is known as the heart's natural pacemaker. The rate of action potentials produced (and therefore the heart rate) is influenced by the nerves that supply it. Structure The sinoatrial node is a oval-shaped structure that is approximately fifteen mm long, three mm wide, and one mm thick, located directly ...
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Sinoatrial Nodal Artery
The sinoatrial nodal artery (or sinuatrial nodal artery or sinoatrial artery) is an artery of the heart which supplies the sinoatrial node, the natural pacemaker center of the heart, and arises from the right coronary artery in around 60% of people. In about 40% of cases, the sinoatrial artery is a branch of the left circumflex coronary artery. In less than 1% of humans, the artery has an anomalous origin directly from the coronary sinus, descending aorta, or distal right coronary artery. In more than 50% of human hearts, the artery actually courses close to the superior posterior aspect of the interatrial septum. The origin of the sinoatrial node artery is not related to coronary artery dominance, which means the side (right or left) that provides the circulation to the back of the heart. In contrast, the atrioventricular nodal branch, that is the artery that brings blood to the atrioventricular node, depends on coronary artery dominance. The sinoatrial node surrounds the sinoatri ...
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Electrical Conduction System Of The Heart
The cardiac conduction system (CCS) (also called the electrical conduction system of the heart) transmits the signals generated by the sinoatrial node – the heart's pacemaker, to cause the heart muscle to contract, and pump blood through the body's circulatory system. The pacemaking signal travels through the right atrium to the atrioventricular node, along the bundle of His, and through the bundle branches to Purkinje fibers in the walls of the ventricles. The Purkinje fibers transmit the signals more rapidly to stimulate contraction of the ventricles. The conduction system consists of specialized heart muscle cells, situated within the myocardium. There is a skeleton of fibrous tissue that surrounds the conduction system which can be seen on an ECG. Dysfunction of the conduction system can cause irregular heart rhythms including rhythms that are too fast or too slow. Structure Electrical signals arising in the SA node (located in the right atrium) stimulate the atr ...
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Collagen
Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such as cartilage, bones, tendons, ligaments, and skin. Depending upon the degree of mineralization, collagen tissues may be rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue and accounts for 6% of the weight of the skeletal muscle tissue. The fibroblast is the most common cell that crea ...
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Blood Vessels
The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away from the tissues. Blood vessels are needed to sustain life, because all of the body's tissues rely on their functionality. There are five types of blood vessels: the arteries, which carry the blood away from the heart; the arterioles; the capillaries, where the exchange of water and chemicals between the blood and the tissues occurs; the venules; and the veins, which carry blood from the capillaries back towards the heart. The word ''vascular'', meaning relating to the blood vessels, is derived from the Latin ''vas'', meaning vessel. Some structures – such as cartilage, the epithelium, and the lens and cornea of the eye – do not contain blood vessels and are labeled ''avascular''. Etymology * artery: late Middle English; from Latin ' ...
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Connective Tissue
Connective tissue is one of the four primary types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue. It develops from the mesenchyme derived from the mesoderm the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. Blood, and lymph are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the body water. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leucocytes. The term "connective tissue" (in German, ''Bindegewebe'') was introduced in 1830 by Johannes Peter Müller. The tissue was already recognized as a distinct class in the 18th century. ...
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Sinoatrial Node 2 Low Mag
The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately fifteen mm long, three mm wide, and one mm thick, located directly below and to the side of the superior vena cava. These cells can produce an electrical impulse an action potential known as a cardiac action potential that travels through the electrical conduction system of the heart, causing it to contract. In a healthy heart, the SA node continuously produces action potentials, setting the rhythm of the heart (sinus rhythm), and so is known as the heart's natural pacemaker. The rate of action potentials produced (and therefore the heart rate) is influenced by the nerves that supply it. Structure The sinoatrial node is a oval-shaped structure that is approximately fifteen mm long, three mm wide, and one mm thick, located directly b ...
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Inferior Vena Cava
The inferior vena cava is a large vein that carries the deoxygenated blood from the lower and middle body into the right atrium of the heart. It is formed by the joining of the right and the left common iliac veins, usually at the level of the fifth lumbar vertebra. The inferior vena cava is the lower (" inferior") of the two venae cavae, the two large veins that carry deoxygenated blood from the body to the right atrium of the heart: the inferior vena cava carries blood from the lower half of the body whilst the superior vena cava carries blood from the upper half of the body. Together, the venae cavae (in addition to the coronary sinus, which carries blood from the muscle of the heart itself) form the venous counterparts of the aorta. It is a large retroperitoneal vein that lies posterior to the abdominal cavity and runs along the right side of the vertebral column. It enters the right auricle at the lower right, back side of the heart. The name derives from la, vena, "vei ...
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Terminal Sulcus (heart)
The terminal sulcus is a groove in the right atrium of the heart. The terminal sulcus marks the separation of the right atrial pectinate muscles from the sinus venarum. The terminal sulcus extends from the front of the superior vena cava to the front of the inferior vena cava, and represents the line of union of the sinus venosus of the embryo with the primitive atrium. On the internal aspect of the right atrium, corresponding to the terminal sulcus is the crista terminalis. The superior border of the terminal sulcus designates the transverse plane in which the SA node resides. The inferior border designates the transverse plane in which the AV node The atrioventricular node or AV node electrically connects the heart's atria and ventricles to coordinate beating in the top of the heart; it is part of the electrical conduction system of the heart. The AV node lies at the lower back section of t ... resides. References External links Cardiac anatomy {{circulatory-stu ...
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Heart
The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest. In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall ...
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Crista Terminalis
The crista terminalis or terminal crest represents the junction between the sinus venosus and the heart in the developing embryo. In the development of the human heart, the right horn and transverse portion of the sinus venosus ultimately become incorporated with and forms a part of the adult right atrium, where it is known as the ''sinus venarum''. The line of union between the right atrium and the right atrial appendage is present on the interior of the atrium in the form of a vertical crest, known as the crista terminalis or ''crista terminalis of His''. The crista terminalis is generally a smooth-surfaced, thick portion of heart muscle in a crescent shape at the opening into the right atrial appendage. On the external aspect of the right atrium, corresponding to the crista terminalis is a groove, the terminal sulcus. The crista terminalis provides the origin for the pectinate muscles. See also * Sinoatrial node The sinoatrial node (also known as the sinuatrial node, SA node ...
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Atrial
The atrium ( la, ātrium, , entry hall) is one of two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles. Each atrium is roughly cube-shaped except for an ear-shaped projection called an atrial appendage, sometimes known as an auricle. All animals with a closed circulatory system have at least one atrium. The atrium was formerly called the 'auricle'. That term is still used to describe this chamber in some other animals, such as the ''Mollusca''. They have thicker muscular walls than the atria do. Structure Humans have a four-chambered h ...
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Sino-
The names of China include the many contemporary and historical appellations given in various languages for the East Asian country known as ''Zhōngguó'' (/, "middle country") in its national language, Standard Mandarin. China, the name in English for the country, was derived from Portuguese in the 16th century, and became common usage in the West in the subsequent centuries. It is believed to be a borrowing from Middle Persian, and some have traced it further back to Sanskrit. It is also thought that the ultimate source of the name China is the Chinese word "Qin" (), the name of the dynasty that unified China but also existed as a state for many centuries prior. There are, however, other alternative suggestions for the origin of the word. Chinese names for China, aside from ''Zhongguo'', include '' Zhōnghuá'' (/, "central beauty"), '' Huáxià'' (/, "beautiful grandness"), ''Shénzhōu'' (, "divine state") and ''Jiǔzhōu'' (, "nine states"). '' Hàn'' (/) and '' Táng'' () ...
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